This study aims to develop Mobile Learning Media (MLM) technology-based learning in learning programming of Computer Numerical Control (CNC) in vocational high schools. This development is important to improve student competence to be ready for work. Product development design uses the ADDIE technique which includes the stages of analysis, design, development, implementation and evaluation. The application of product development was carried out by using an experimental trial method with a random control group pretest-postest design. The number of research respondents are 120 students with 60 students in the experimental class and 60 students in the control class. Research data includes data on students' learning outcomes and interview data with students after the application of the use of mobile learning which has been developed. Analysis of research data used descriptive statistical techniques and independent sample T-test by using SPSS 2.0 software. The results showed that the use of MLM can facilitate students to learn anywhere and anytime. MLM in CNC learning can provide real learning on how the CNC program is run, so that it can increase students' motivation and learning achievement. MLM supports students' independent learning and makes students become more confident in mastering their competencies, so that teachers can do a variety of jobs easily.