Smartphone assisted colorimetric and fluorescent triple-channel signal sensor for ascorbic acid assay based on oxidase-like CoOOH nanoflakes

Polyoxometalate Nanostructures Decorated with CuO Nanoparticles for Sensing Ascorbic Acid and Fe2+ Ions

“…To date, a great deal of methods for detecting AA and Fe 2+ have been reported; however, many problems still exist such as tedious prepreparation procedures, time consuming, and low sensitivity and bad selectivity. Based on the characteristics of the enzyme, new technologies have been developed for food analysis combined with various bioengineering .…”

Self-enhanced peroxidase-like activity in a wide pH range enabled by heterostructured Au/MOF nanozymes for multiple ascorbic acid-related bioenzyme analyses

“…At present, multiple methods have been exploited for AA and AA-related bio-enzyme determination. 19,20 However, these existing strategies often have some disadvantages such as complex operating systems, large sample consumption, high technical requirements, or weak signals that cannot be read directly. It is well-known that signal changes based on the reac-tion of enzyme mimics with biomolecules have attracted extensive attention.…”

In situ construction of a cobalt oxyhydroxide loaded pyrene-based fluorescent organic nanoprobe for bioimaging of endogenous ascorbic acid in living cells

“…30 Among the detection assays, the CoOOH nanoflake-based nanohybrid biosensing platform offers a new opportunity for monitoring and imaging at the cellular level through an intrinsic optical signal change of nanoprobes upon their interaction with AA. Until now, a variety of CoOOH nanoflake-based nanoprobes have been developed by using some kinds of nanofluorophores such as persistent luminescence nanoparticles (PLNPs), 31 carbon nanomaterials, 32,33 and lanthanide-doped upconverting nanoparticles (UCNPs). 34 These probes, however, are arguably complicated and have harsh fabrication processes, due to the attenuation time and intensity of PLNPs, and the thermal tissue damage under near-infrared luminescence irradiation for a long time.…”