Smart Nanomaterials

Davis, Frank; Shimizu, Flávio M.; Altıntaş, Zeynep

doi:10.1002/9781119065036.ch11

Cited by 4 publications

(2 citation statements)

References 323 publications

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“…The need for wearable smart sensors for biomedical applications is growing rapidly and is expected to reach a revenue of USD 97.8 billion by 2023 [ 120 ]. Nanomaterials have been explored extensively for smart sensor devices [ 121 , 122 ], and since its discovery, graphene has been utilized as a base material for a variety of smart devices [ 123 , 124 ]. Recently, MXenes with superior electrochemical properties emerged as a viable alternative to graphene in smart devices.…”

Section: Biosensor and Smart Sensor Applicationsmentioning

confidence: 99%

Advances of MXenes; Perspectives on Biomedical Research

2022

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The last decade witnessed the emergence of a new family of 2D transition metal carbides and nitrides named MXenes, which quickly gained momentum due to their exceptional electrical, mechanical, optical, and tunable functionalities. These outstanding properties also rendered them attractive materials for biomedical and biosensing applications, including drug delivery systems, antimicrobial applications, tissue engineering, sensor probes, auxiliary agents for photothermal therapy and hyperthermia applications, etc. The hydrophilic nature of MXenes with rich surface functional groups is advantageous for biomedical applications over hydrophobic nanoparticles that may require complicated surface modifications. As an emerging 2D material with numerous phases and endless possible combinations with other 2D materials, 1D materials, nanoparticles, macromolecules, polymers, etc., MXenes opened a vast terra incognita for diverse biomedical applications. Recently, MXene research picked up the pace and resulted in a flood of literature reports with significant advancements in the biomedical field. In this context, this review will discuss the recent advancements, design principles, and working mechanisms of some interesting MXene-based biomedical applications. It also includes major progress, as well as key challenges of various types of MXenes and functional MXenes in conjugation with drug molecules, metallic nanoparticles, polymeric substrates, and other macromolecules. Finally, the future possibilities and challenges of this magnificent material are discussed in detail.

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Section: Biosensor and Smart Sensor Applicationsmentioning

confidence: 99%

Advances of MXenes; Perspectives on Biomedical Research

2022

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“…Hence, they are termed stimuli-responsive smart materials. Furthermore, they have a large surface area withal swelling translation, biocompatibility, and stability [241]. Based on the function of nanogels in a biosensing system, their applications can be categorised into: (i) encapsulation vehicles; (ii) multifunctional stimuli-responsive materials; and (iii) sensory membranes [242].…”

Section: Organic Nanomaterials Applications For Healthcare Biosensingmentioning

confidence: 99%

Nanomaterials for Healthcare Biosensing Applications

Pirzada

Altıntaş

2019

Sensors

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173

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In recent years, an increasing number of nanomaterials have been explored for their applications in biomedical diagnostics, making their applications in healthcare biosensing a rapidly evolving field. Nanomaterials introduce versatility to the sensing platforms and may even allow mobility between different detection mechanisms. The prospect of a combination of different nanomaterials allows an exploitation of their synergistic additive and novel properties for sensor development. This paper covers more than 290 research works since 2015, elaborating the diverse roles played by various nanomaterials in the biosensing field. Hence, we provide a comprehensive review of the healthcare sensing applications of nanomaterials, covering carbon allotrope-based, inorganic, and organic nanomaterials. These sensing systems are able to detect a wide variety of clinically relevant molecules, like nucleic acids, viruses, bacteria, cancer antigens, pharmaceuticals and narcotic drugs, toxins, contaminants, as well as entire cells in various sensing media, ranging from buffers to more complex environments such as urine, blood or sputum. Thus, the latest advancements reviewed in this paper hold tremendous potential for the application of nanomaterials in the early screening of diseases and point-of-care testing.

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