„Smart eye data“

Kortüm, Karsten; Müller, Michael; Hirneiß, Christoph; Babenko, Alexander; Nasseh, Daniel; Kern, Christoph; Priglinger, Siegfried; Kreutzer, Thomas C.

doi:10.1007/s00347-016-0272-2

Cited by 13 publications

(6 citation statements)

References 18 publications

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“…23 Numerous studies have evaluated handheld cameras for detecting diabetic retinopathy with relatively high sensitivities and specificities. [24][25][26] Nevertheless, these devices have their own sets of limitations, such as the need for consistent manual alignment to maintain focus, and issues with light reflexes on the condensing lens. 12,27 The most affordable option among direct ophthalmoscopes is the handheld PanOptic, while the Versacam provides the best FOV (45°) (Table 1 and 2).…”

Section: Limitations Of Digital Ophthalmoscopesmentioning

confidence: 99%

A Systematic Review of Digital Ophthalmoscopes in Medicine

Robles,

Patel,

Neag

et al. 2023

OPTH

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Purpose Recent advances in telemedicine have led to increased use of digital ophthalmoscopes (DO) in clinical settings. This review aims to assess commercially available DOs, including smartphone (SP), desktop, and handheld ophthalmoscopes, and evaluate their applications. Methods A literature review was performed by searching PubMed (pubmed.ncbi.nlm.nih.gov), Web of Science (webofknowledge.com), and Science Direct (sciencedirect.com). All English-language papers that resulted from the search terms “digital ophthalmoscope”, “screening tool”, “glaucoma screening”, “diabetic retinopathy screening”, “cataract screening”, and “papilledema screening” were reviewed. Studies that contained randomized clinical trials with human participants between January 2010 and December 2020 were included. The Risk of Bias in Systematic Reviews (ROBIS) tool was used to assess the methodological quality of each included paper. Results Of the 1307 studies identified, 35 met inclusion and exclusion criteria. The ROBIS tool determined that 29/35 studies (82.8%) had a low risk of bias, 3/35 (8.5%) had a moderate risk of bias, and 3/35 (8.5%) had a high risk of bias. Conclusion The continued adoption of DOs remains uncertain because of concerns about the image quality for non-mydriatic eyes and the confidence in data captured from the device. Likewise, there is a lack of guidelines for the use of DOs, which makes it difficult for providers to determine the best device for their practice and to ensure appropriate use. Even so, DOs continue to gain acceptance as technology and practice integration improve, especially in underserved areas with limited access to ophthalmologists.

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Section: Limitations Of Digital Ophthalmoscopesmentioning

confidence: 99%

A Systematic Review of Digital Ophthalmoscopes in Medicine

Robles,

Patel,

Neag

et al. 2023

OPTH

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“…This warehouse contains clinical findings from the patients' EHR; a customized version of i.s.h. med (Cerner AG, Erlangen, Germany) and investigation results for more than 393,000 patients as of February 2020 [14]. Moreover, all digital movements of the patients in the clinic are recorded with a timestamp (start of registration, consultation, and diagnostics).…”

Section: Data Sourcementioning

confidence: 99%

Big data simulations for capacity improvement in a general ophthalmology clinic

Kern

König

et al. 2021

Graefes Arch Clin Exp Ophthalmol

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Purpose Long total waiting times (TWT) experienced by patients during a clinic visit have a significant adverse effect on patient’s satisfaction. Our aim was to use big data simulations of a patient scheduling calendar and its effect on TWT in a general ophthalmology clinic. Based on the simulation, we implemented changes to the calendar and verified their effect on TWT in clinical practice. Design and methods For this retrospective simulation study, we generated a discrete event simulation (DES) model based on clinical timepoints of 4.401 visits to our clinic. All data points were exported from our clinical warehouse for further processing. If not available from the electronic health record, manual time measurements of the process were used. Various patient scheduling models were simulated and evaluated based on their reduction of TWT. The most promising model was implemented into clinical practice in 2017. Results During validation of our simulation model, we achieved a high agreement of mean TWT between the real data (229 ± 100 min) and the corresponding simulated data (225 ± 112 min). This indicates a high quality of the simulation model. Following the simulations, a patient scheduling calendar was introduced, which, compared with the old calendar, provided block intervals and extended time windows for patients. The simulated TWT of this model was 153 min. After implementation in clinical practice, TWT per patient in our general ophthalmology clinic has been reduced from 229 ± 100 to 183 ± 89 min. Conclusion By implementing a big data simulation model, we have achieved a cost-neutral reduction of the mean TWT by 21%. Big data simulation enables users to evaluate variations to an existing system before implementation into clinical practice. Various models for improving patient flow or reducing capacity loads can be evaluated cost-effectively.

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“…Clinical information was extracted from a data warehouse that has been active since 2012. 19 It contains clinical findings from the patients' electronic health record (EHR) and investigative results of more than 330,000 patients. 20 This includes retinal thickness and volume values in the nine circular macular grids defined by the ETDRS study group obtained from optical coherence tomography (OCT) imaging (SPECTRALIS, Heidelberg Engineering, Heidelberg, Germany).…”

Section: Data Source and Patient Characteristicsmentioning

confidence: 99%

<p>Two Year Visual Acuity and Structural Outcomes in Patients with Diabetic Macular Oedema Treated with Intravitreal Aflibercept – A Retrospective Cohort Study</p>

Kern¹,

Schiefelbein²,

Fu³

et al. 2020

OPTH

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Purpose: To assess visual and anatomical outcomes of intravitreal aflibercept for clinically significant diabetic macular oedema (DME). Methods: For this retrospective single-center cohort study at a tertiary referral center, we performed a data warehouse query to identify 117 treatment-naive patients (139 eyes) undergoing intravitreal treatment with aflibercept for DME between January 2014 and May 2018. Changes in best-corrected visual acuity (BCVA) values (as measured with ETDRS letters), central retinal thickness (CRT) and total macular volume (TVOL) are reported over a two-year period at various time-points. Results: The total number of injections per study eye was 5.5 ± 1.4 after one and 8.7 ± 2.2 injections after two years. Baseline visual acuity (VA) was 60.1 ± 14.5 letters. A gain of 4.8 and 9.2 letters from baseline was observed after one and two years, respectively (both p ≤ 0.01). In comparison to the mean CRT at baseline (419 ± 174 µm), a CRT decrease was observed after one and two years of treatment (298 ± 115 µm and 319 ± 119 µm, respectively; both p ≤ 0.01). Similarly, TVOL decreased from 10.12 ± 2.05 mm 3 to 8.96 ± 0.96 mm 3 and 9.01 ± 1.29 mm 3 (both p ≤ 0.01). Conclusion: This study demonstrates that treating DME with intravitreal aflibercept yields positive functional and structural outcomes over a two-year period. However, we observed fewer injection numbers, along with inferior VA and structural outcomes than has been reported in randomized clinical trials. Our results show similar results as in patients treated with ranibizumab due to DME in real-life settings.

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„Smart eye data“

Abstract: By building a DW a foundation for clinical and epidemiological studies could be implemented. In the future, decision support systems and strategies for personalized therapies can be based on such a database.

Cited by 13 publications

References 18 publications

A Systematic Review of Digital Ophthalmoscopes in Medicine

A Systematic Review of Digital Ophthalmoscopes in Medicine

Big data simulations for capacity improvement in a general ophthalmology clinic

<p>Two Year Visual Acuity and Structural Outcomes in Patients with Diabetic Macular Oedema Treated with Intravitreal Aflibercept – A Retrospective Cohort Study</p>

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