Small Vessel Myography

Kamishima, Tomoko; Quayle, J. M.

doi:10.1002/9781118402184.ch5

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2014

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“…The need to accurately measure physiological functions and properties of small arteries, veins and other vessels is well established [1]. Vascular smooth muscle cells, located inside vessel wall play a key role in contraction and relaxation of arteries [2].…”

Section: Introductionmentioning

confidence: 99%

Optical Feedback Interferometry sensor for flow characterization inside ex-vivo vessel

Quotb

Ramírez-Miquet

Tronche

et al. 2014

IEEE SENSORS 2014 Proceedings

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Pressure myograph systems allow the study of pharmacological effects of drugs and other vasoactive compounds on small isolated vessels by image processing. In this work, we present a new pressure myograph system based on Optical Feedback Interferometry (OFI) sensor that gives information about local velocity in fluids and enables reconstruction of a velocity profile inside a vessel. OFI is a self-aligned interferometric technique that uses the laser as both the light source and the receiver thus offering high sensitivity, fast response, and a simple and compact optical design. The local Doppler flow velocity is directly measured inside ex-vivo rat vessel with a step of 100 µm thus avoiding the need to use complex image processing and models based profile calculation for extracting flow velocity. This technique will be useful to investigate hemodynamics in microcirculation by measuring unsteady irregular blood.

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Section: Introductionmentioning

confidence: 99%