Small Thymomas and Myasthenia Gravis: a Poorly Understood Association

Christiansen, Stefan; Marx, Alexander; Kiefer, Reinhard; Hh, Scheld; Semik, M

doi:10.1055/s-2000-9938

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(Top) All Cases Shown As Stacked Columns Comparing Tumors F1

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“…23 It appears that MG was also diagnosed in about 20% of patients with a thymoma, which is confirmed by another study. 24 Higher estimates are also reported 25,26 ; however, this may be explained by selection bias. Unlike in other patients, thymomas are intensively searched for in MG by radiologic examinations and also are frequently found due to the management practice of performing thymectomy.…”

Section: (Top) All Cases Shown As Stacked Columns Comparing Tumors Fmentioning

confidence: 86%

The occurrence of anti-titin antibodies and thymomas

Somnier

Engel²

2002

Neurology

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Apart from MG with a thymoma, the finding of the titin autoantibodies was observed to be an exclusive feature of late-onset MG, the frequency being 55%. No data were found to suggest that patients with MG were more likely to present with thymic tumors than other patients exhibiting thymic neoplasia. In about 80%, such tumors in MG were composed of cortical cells. The concept of the anti-titin antibodies merely as a paraneoplastic marker in MG was not supported by these data.

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