2020
DOI: 10.1016/j.jhazmat.2019.121221
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Small-scale wastewater treatment plants as a source of the dissemination of antibiotic resistance genes in the aquatic environment

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Cited by 201 publications
(84 citation statements)
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“…The copy numbers of nearly all analyzed ARGs were lowest in URW samples. Similarly to this study, numerous researchers have reported on the widespread presence of ARGs in both TWW and the receiving water bodies [ 29 , 51 , 54 , 57 , 58 , 59 , 60 , 61 , 62 , 63 ]. Mao et al [ 61 ] observed an increase in the copy numbers of ARGs during wastewater treatment in WWTPs.…”
Section: Resultssupporting
confidence: 63%
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“…The copy numbers of nearly all analyzed ARGs were lowest in URW samples. Similarly to this study, numerous researchers have reported on the widespread presence of ARGs in both TWW and the receiving water bodies [ 29 , 51 , 54 , 57 , 58 , 59 , 60 , 61 , 62 , 63 ]. Mao et al [ 61 ] observed an increase in the copy numbers of ARGs during wastewater treatment in WWTPs.…”
Section: Resultssupporting
confidence: 63%
“…The present results corroborate the findings of other authors who reported on the dominance of the int I1 gene among integrase-encoding genes in environmental samples [ 67 ]. Integrons are ubiquitous in TWW [ 25 , 32 , 68 , 69 ] and in rivers such as the Vistula, Warta, and Łyna [ 29 , 60 , 70 , 71 ]. These genetic structures promote rapid bacterial evolution by enabling bacteria to accumulate, express, and transfer coding sequences such as ARGs [ 67 , 72 ].…”
Section: Resultsmentioning
confidence: 99%
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“…This phenomenon is associated with the significant decrease in the number of new types of antibiotics introduced in the last decades, as well as with the increasing consumption of conventional antibiotics in both human and animal medicine worldwide [1]. It is well known that many of these antibiotics, once arrived in municipal wastewater, cannot be completely removed in conventional wastewater treatment plants being an important source of contamination of natural water bodies [2,3]. These can affect indigenous microbial populations by disrupting the natural balance of that environment, and may even increase the resistance of certain species of bacteria to these antibiotics.…”
Section: Introductionmentioning
confidence: 99%
“…Globally, multi-drug resistant bacteria is an emerging public health crisis [29]. Wastewater treatment plant serves as a remarkable source of antibiotic resistant intestinal bacteria and antibiotic resistant genes, which may transfer to other environmental bacteria [30]. Hence, the determination of antibiotic resistance profile of selected bacteria is necessary for large scale implementation of these bacteria in treatment plants.…”
Section: Sensitivity To Antibioticsmentioning
confidence: 99%