Abstract:Leaves of higher plants exhibit a varying degree of asymmetry along their dorsoventral axis. This asymmetry is specified via the polarized expression of class III homeodomain‐leucine zipper (hd‐zipIII) genes, which specify dorsal cell fate. Through detailed in situ hybridization analyses we were able to show that this polarized hd‐zipIII expression is set up by the graded expression pattern of a 21‐nucleotide microRNA, miR166. More recently, we have shown that this miR166 gradient is generated through the oppo… Show more
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