Small RNA sequencing analysis of exosomes derived from umbilical plasma in IUGR lambs
Jiawei Lu,
Huixia Li,
Xiaomin Zheng
et al.
Abstract:During the summer, pregnant ewes experience heat stress, leading to the occurrence of IUGR lambs. This study aims to explore the biomarkers of exosomal miRNAs derived from umbilical plasma in both IUGR and normal Hu lambs. We establish a heat-stressed Hu sheep model during mid-late gestation and selected IUGR and normal lambs for analysis. Exosomes from umbilical plasma were separated and small RNA sequencing is used to identify differentially expressed miRNAs. Next, we utilize MiRanda to predict the target ge… Show more
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