Small Noncoding RNA AbcR1 Addressing Multiple Target mRNAs From Transcriptional Factor and Two-Component Response Regulator of Brucella melitensis

Abstract

Background: AbcR, as a small noncoding RNA (sRNA), is a typical example of a molecule acting on transencoded target mRNAs. It

Small non-coding RNAs in virulence and immunity of Brucella

“…9 The conserved seed region of AbcR1 is responsible for regulating multiple target mRNAs belonging to transcriptional factor and two component response regulator of Brucella melitensis. 10 A BSR0602 sRNA directly target gntR mRNA and play important roles in bacterial adaptation to stress conditions and thus facilitates the intracellular survival of Brucella. 11 A large number of Brucella sRNA was identified using strand-specific RNA deep-sequencing approach, and BSR0441 was further characterized that involved in the virulence and stress adaptation of Brucella.…”