Small Intestine Biopsy and its Interpretation: Preliminary Results in Costa Rica

Brenes, Fernando; Herrera, Adelita

doi:10.3926/oms.229

Cited by 3 publications

(3 citation statements)

References 19 publications

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“…The celiac disease histological alterations, morphological changes, grading the presence of immunological disorders with architectural changes of the mucosa is integrated in Oberhuber classification. [6] The initial diagnosis for the 200 cases according to Marsh Oberhuber classification were as follows in the figure 1. When reclassified according to the Marsh Oberhuber classification, following were the results of both the pathologists as shown in the figure 2 and 3.…”

Section: Resultsmentioning

confidence: 99%

Celiac Disease: Comparison of Oberhuber Classification and Corazza- Villanacci Classification

Ghanghoria

Sharma

Jain

2019

APALM

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Background: Celiac disease occurs in genetically predisposed individuals on consumption of certain grains. The diagnosis is based on biopsy showing the presence of characteristic histological changes in duodenum and jejunum that improve after gluten free diet. The Oberhuber Classification is very widely used by pathologists. The new Corazza-Villanacci Classification simplifies the criteria.Methods: Retrospectively diagnosed 200 patients of Celiac disease according to Oberhuber classification over duration of 05 years were considered. The 200 cases were retrieved from the records and were sent to two pathologists, who were blinded to each other and were not given any clinical information. Each pathologist received the set of biopsy specimens on two separate occasions and had reclassified them according to both grading systems in a random order. The interobserver variation was then determined after re-examination according to Oberhuber classification and after using to Corazza-Villanacci classification too Result: Mean kappa values were 0.77 (good) for the Oberhuber classification versus 0.98 (very good) for the Corazza -Villanacci classification Conclusion:The Corazza-Villanacci classification gives better interobserver agreement compared with the Oberhuber classification and contributes to the validity of diagnosis in celiac disease.

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Section: Resultsmentioning

confidence: 99%

Celiac Disease: Comparison of Oberhuber Classification and Corazza- Villanacci Classification

Ghanghoria

Sharma

Jain

2019

APALM

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“…Interestingly 15 of the 36 patients turned out to be negative, and had lymphocytic duodenitis. Further follow-up of these patients is needed since the differential diagnosis for lymphocytic duodenitis is extensive and several known causes have not yet been excluded [ 2 ].…”

Section: Resultsmentioning

confidence: 99%

“…The tests used for diagnosis have been specific serological markers and intestinal biopsy through upper gastrointestinal endoscopy. According to recent available literature in only a small series of patients determination of the human leukocyte antigen (HLA)-based genetic susceptibility to celiac disease took place in El Salvador [ 1 ] and Costa Rica [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Central America in Transition: From Maize to Wheat Challenges and Opportunities

Peña

Crusius

2015

Nutrients

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The Central American countries: Guatemala, El Salvador, Honduras, Nicaragua, Costa Rica, and Panama are in transition from a dietary culture based mainly on maize to a wheat-containing diet. Several other changes are occurring, such as a decrease of parasitic and infectious diseases. The environmental changes permit a prediction of an increase of celiac disease and other autoimmune diseases such as type I diabetes and thyroid disease in these genetically heterogeneous countries. At present, celiac disease and gluten-related disorders are considered to be of no relevance at the level of public health in these nations. This review documents the presence of celiac disease in Central America. It draws attention to some of the challenges in planning systematic studies in the region since up until recently celiac disease was unknown. The aim of this review is to disseminate knowledge obtained with preliminary data, to stimulate clinical and basic scientists to study these diseases in Central America and to alert authorities responsible for the planning of education and health, to find possibilities to avoid a rise in these disorders before the epidemics start, as has occurred in the Mediterranean countries.

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Epidemiology of Celiac Disease and Non-Celiac Gluten-Related Disorders

Peña¹,

Rodrigo²

2015

Advances in the Understanding of Gluten Related Pathology and the Evolution of Gluten-Free Foods

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Small Intestine Biopsy and its Interpretation: Preliminary Results in Costa Rica

Cited by 3 publications

References 19 publications

Celiac Disease: Comparison of Oberhuber Classification and Corazza- Villanacci Classification

Celiac Disease: Comparison of Oberhuber Classification and Corazza- Villanacci Classification

Central America in Transition: From Maize to Wheat Challenges and Opportunities

Epidemiology of Celiac Disease and Non-Celiac Gluten-Related Disorders

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