Small Incision Lenticule Extraction (SMILE)

Sekundo, Walter

doi:10.1007/978-3-319-18530-9

Cited by 16 publications

(2 citation statements)

References 5 publications

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“…Laser irradiation of the cornea by CPV Tx is a new corneal laser procedure that differs from invasive corneal procedures such as conductive keratoplasty (CK) 14 , laser-assisted in situ keratomileusis (LASIK) 15 , laser thermal keratoplasty (LTK) 16 and small incision lenticule extraction (SMILE) 17 in many ways including that, for CPV Tx, no corneal tissue is punctured, cut or removed and the epithelium is protected from thermal damage. The laser is "eye safe" meaning that the laser light is completely absorbed in the cornea; none of the laser light propagates through the cornea to irradiate the lens or the retina.…”

Section: Discussionmentioning

confidence: 99%

Corneal laser procedure for vision improvement in patients with late stage dry age-related macular degeneration - a retrospective observational cohort study

Stein¹,

Markowitz

Berry

2020

F1000Res

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Purpose: To determine the safety and efficacy of corneal photovitrification (CPV), a new corneal laser procedure, for vision improvement in patients with late stage dry age-related macular degeneration (AMD). Design: Retrospective observational cohort study Participants: 32 eyes of 17 patients with late stage dry AMD; each eye received a single CPV corneal laser procedure and had 12 months (12m) post-treatment (Tx) follow-up. Methods: Pre- and post-Tx examinations included slit-lamp biomicroscopy, subjective manifest refraction, best corrected distance and near visual acuity (BCDVA and BCNVA), and potential visual acuity (PVA). Additional examinations including contrast sensitivity (CS), corneal topography (CT), ray tracing aberrometry (RTA) and microperimetry (MP) were obtained for a subgroup (n=12) of eyes. Main Outcome Measures: BCDVA, BCNVA, PVA, CS, CT, RTA and MP measurements Results: Safety – There were no complications or adverse events. Efficacy – Mean (± SD) BCDVA improved significantly (p < 0.004) from 20/238 (1.08 logMAR) at baseline to 20/144 (0.86 logMAR) at 12m post-Tx corresponding to 11.0 (± 13.1) letters gained. Mean contrast sensitivity improved significantly (p < 0.05) by a factor of 1.86 from baseline at 12m post-Tx. Conclusions: Subject to the limitation of a small sample size, this pilot study indicates that the CPV corneal laser procedure is safe and efficacious for vision improvement in patients with late stage dry AMD. The CPV Tx mechanism of action involves retinal irradiance distribution modifications that may stimulate patient use of functional, rather than atrophied, retinal regions.

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Section: Discussionmentioning

confidence: 99%

Corneal laser procedure for vision improvement in patients with late stage dry age-related macular degeneration - a retrospective observational cohort study

Stein¹,

Markowitz

Berry

2020

F1000Res

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“…The femto-LASIK is nowadays a standard treatment for the correction of myopia, hyperopia, and astigmatism. Other modern laser-surgeries like the SMILE (Small Incision Lenticule Extraction) treatment are an all-fs-laser solution without the UV-excimer laser source and flap creation [31]. To further increase the quality, approaches with finer laser focusing and lower pulse energies are tested and show good results.…”

Section: Ophthalmologymentioning

confidence: 99%

X-ray emission during the ablative processing of biological materials by ultrashort laser pulses

et al. 2023

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The ablative laser processing with ultrashort pulsed laser beams may cause secondary emission of hazardous X-rays. While the effect has recently been proven to be considered in working safety regulations when processing technical materials, such as metals, the X-ray emission rates during the ablative processing of biological tissue materials are widely unexplored yet. Therefore, biological materials like water, isotonic saline solution, pig eyes, and human teeth were ablated with ultrashort laser pulses of 1030 nm wavelength, 600 fs pulse duration and 5 kHz pulse repetition rate, aiming to mimic typical surgery situations. Simultaneously, in-situ X-ray dose rate measurements were performed at a short distance from the plasma to display potential X-ray emission. For all four studied biological materials, our measurements prove the secondary emission of laser-induced X-rays.

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