Small Doses of Subcutaneous Sodium Heparin in Preventing Deep Venous Thrombosis After Major Surgery

Controlled Trial of Platelet Anti-Aggregating Agents and Subcutaneous Heparin in Prevention of Postoperative Deep Vein Thrombosis in High Risk Patients

“…Several studies [5,6,9,11,14,25] have now confirmed that a standard regimen of low-dose heparin is quite effective in preventing DVT in patients undergoing a variety of general abdominal operations. However, the results have been less encouraging in patients undergoing total hip replacement; in a study reported by K a k k a r et al [11], 4 (27%) of 15 such patients devel oped thrombosis.…”

“…Several recent trials [2,5,6,9,11,12,14,25] have demonstrated that low-dose heparin prophylaxis significantly reduces the incidence of deep vein thrombosis (DVT) detected by the 125I-fibrinogen test. In other controlled trials, heparin prophylaxis has been shown to be more effective than oral anticoagulants [23] or pre-and postoperative infusion of Dextran 70 [24],…”

Prevalence of deep venous thrombosis in the lower extremities of children in the intensive care unit

“…In one small prospective study, 4 of 54 children on halo-femoral traction had DVT [14]. This is in contrast to the incidence of DVT in hospitalized adults who received no prophylaxis (from 30 % overall in high-risk patients [15,16] to 40-60 % in adults with a hip fracture or arthroplasty [17][18][19]). …”

Combined Administration of Low Dose Heparin and Aspirin as Prophylaxis of Deep Vein Thrombosis after Hip Joint Surgery

“…Several trials demonstrated that low doses of subcutaneous heparin can reduce thromboembolic diseases in general surgical patients [4,5,11,13,21]. But recent studies revealed that the low dose heparin (LDH) is not effec tive enough to prevent DVT after hip joint surgery [2,6,17,18].…”