Small Cell Carcinoma Rectum With Liver Metastases: A Case Report

Ashfaque, Mohammad; Varghese, T. P.; Shanbag, Venkatesh; Soma, Srikanth

doi:10.9790/0853-1345101102

Cited by 1 publication

(3 citation statements)

References 9 publications

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“…Published reports of colonic SCC and liver metastasis are rare [ 2 , 4 , 5 , 8 ]. Nonetheless, the liver is the most common site of distant metastases from colonic SCC (incidence, 37.5–87.5%) [ 1 , 4 ].…”

Section: Discussionmentioning

confidence: 99%

“…Due to the limited number of cases, no consensus guidelines exist for colonic SCC. Limited reports have shown favorable results for patients treated with a platinum-based drug plus either etoposide or irinotecan [ 2 , 4 ]. Radiation may also extend survival.…”

Section: Discussionmentioning

confidence: 99%

“…Colonic small cell carcinomas (SCCs) are rare, aggressive tumors with early metastasis and poor prognosis [ 1 ]. Approximately 100 reports have been published on SCC [ 2 ]. Its incidence comprises 0.1% of colorectal cancers [ 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Metachronous metastatic colonic small cell carcinoma and recurrent adenocarcinoma in a patient with ulcerative colitis

Elias

Colibaseanu

Croome

2017

Journal of Surgical Case Reports

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Colonic small cell carcinomas (SCCs) are rare, aggressive tumors characterized by early metastasis and poor prognosis. We describe a 39-year-old man with a history of ulcerative colitis and left colon adenocarcinoma resected at an outside institution who presented with hematochezia and proctalgia. Work-up revealed left colon SCC with liver metastases. After his excellent response to neoadjuvant chemotherapy, we performed synchronous proctocolectomy and right hepatectomy. Final pathologic evaluation revealed colonic primary SCC and recurrent adenocarcinoma with metastatic SCC to the liver; lymph nodes were positive for metastatic SCC and adenocarcinoma. SCC recurrence ultimately developed in the liver. To the best of our knowledge, this is the second reported case of surgical management of SCC of the colon with liver metastasis and the first report of synchronous excision. Despite superb response to neoadjuvant therapy and young patient age, caution is needed in surgical resection for SCC of the colon given the high recurrence risk.

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