Small brown circles: An important diagnostic clue for pigmented squamous cell carcinoma

Reflectance confocal microscopy: non‐invasive distinction between actinic keratosis and squamous cell carcinoma

“…observed with RCM the appearance of round circles with a bright white rim at the level of the dermal-epidermal junction corresponding to the small brown circles that can be observed with dermoscopy in pigmented SCC. 44 Unfortunately, we were not able to confirm this observation since this study only revealed non-pigmented lesions. In a larger prospective study, it would be interesting to include pigmented lesions as well.…”

Pigmented squamous cell carcinoma: case report and importance of differential diagnosis

“…Features such as honeycomb-like circles, peripheral streak-like projections, brown spots, and scales were found. 16 , 17 …”

Dermoscopy of verrucous epidermal nevus: large brown circles as a novel feature for diagnosis

“…Kittler et al . described brown lines and circles in seborrheic keratosis, and Fraga‐Braghiroli et al . reported “small brown circles” in pigmented squamous cell carcinoma.…”

“…The brown circles seen in dermoscopy are not exclusive to epidermal nevi. Kittler et al 12 described brown lines and circles in seborrheic keratosis, and Fraga-Braghiroli et al 13 reported small brown circles in pigmented squamous cell carcinoma. Small brown circles are located at the periphery of the lesion and represent, histopathologically, atypical pigmented basal keratinocytes along the rete ridges.…”