Small bowel sarcoma: Tumor biology and advances in therapeutics

Shenoy, Santosh

doi:10.1016/j.suronc.2015.08.002

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Cited by 6 publications

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“…1,2 GISTs occcur in 10-13/million annually and represent the predominant type of gastrointestinal sarcoma (85 %) and the most common single subtype (18 %) of all sarcomas. [3][4][5] GISTs derive from or exhibits differentiation to the interstitial cells of Cajal which are located in the gut wall. 6,7 These cells are consider the pacemaker of the gastrointestinal tract as they organize the interaction between the gut's autonomic nervous system and smooth muscle cells to regulate the motility and peristaltic movement.…”

Section: Introductionmentioning

confidence: 99%