Small bowel liposarcoma--a rare cause of small bowel perforation

Abstract

SummaryA 76-year-old patient was admitted with right-sided lower abdominal pain. CT scan of the abdomen demonstrated a fatty mass arising around the bowel in the left iliac fossa causing local distortion of the vasculature.His clinical condition rapidly deteriorated with worsening abdominal signs necessitating an exploratory laparotomy. A segment of perforated small bowel associated with mesenteric mass was excised and the patient died 3 days later.The histology demonstrated a well-differentiated liposarcoma. Liposarcomas are the most common soft tissue sarcomas in adults but occurrence in the gastrointestinal tract is extremely rare. The clinical presentation of these tumours is frequently non-specific and commonest symptoms are generalised, intermittent abdominal pain.Surgical resection with clear margins is the treatment of choice for primary liposarcomas. They are moderately radiosensitive and chemotherapy is non-effective.Although gastrointestinal liposarcomas have been previously reported, this is the first reported case of a primary liposarcoma associated with a small bowel perforation. BACKGROUND

Intestinal liposarcoma: an unusual cause for peritonitis

“…The tumour had perforated causing peritonitis which was similar to our study. 7 Surgical resection with adequate clear margins is the treatment of choice for all primary liposarcomas which was achieved in our case. 8…”

Primary duodenal dedifferentiated liposarcoma: A case report and literature review

“…The retroperitoneum is the most common location and occurrence in the extremities and subcutaneous tissue is very rare[ 16 ]. Since DDLPS primarily involving the intestine is extremely unusual, less than 10 cases have been reported to date[ 1 - 3 , 5 - 10 , 17 ]. Of those tumors arising in the small bowel, four originated in the jejunum, five in the ileum, and two in the duodenum (Table 1 ).…”

A rare case of primary small bowel de-differentiated liposarcoma causing intussusception

“…[ 1 ] In the present case, de-differentiated primary LPS of the ileum with intussusception was extremely unusual. To the best of our knowledge, there are only 5 case reports of LPS from small bowel [ 2 , 7 – 9 ] and only our report of intussusception caused by it (Table 1 ).…”