2019
DOI: 10.3390/jcm8101748
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Small Bowel—Key Player in Health and Disease

Abstract: Over the last two decades, remarkable progress has been made in understanding the etiology and pathophysiology of diseases [...]

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“…In 1915, Walter Alwarez of the Mayo Clinic popularized the term "functional dyspepsia", the most common disorder from the group of functional disorders. Reported dyspeptic ailments are not correlated with specific physiological disorders, although a relationship has been found between the symptoms of premature satiety and disorders of gastric accommodation, in gastroduodenitis, genetic studies are also carried out, or links between bacterial inflammation of the upper and lower gastrointestinal tract and functional disorders [17][18][19][20][21][22][23][24]. There are no objective diagnostic tools; the symptomatic criteria for functional disorders based on the Roman Criteria are expert consensus excluding organic causes of ailments [25][26][27].…”
Section: Discussionmentioning
confidence: 99%
“…In 1915, Walter Alwarez of the Mayo Clinic popularized the term "functional dyspepsia", the most common disorder from the group of functional disorders. Reported dyspeptic ailments are not correlated with specific physiological disorders, although a relationship has been found between the symptoms of premature satiety and disorders of gastric accommodation, in gastroduodenitis, genetic studies are also carried out, or links between bacterial inflammation of the upper and lower gastrointestinal tract and functional disorders [17][18][19][20][21][22][23][24]. There are no objective diagnostic tools; the symptomatic criteria for functional disorders based on the Roman Criteria are expert consensus excluding organic causes of ailments [25][26][27].…”
Section: Discussionmentioning
confidence: 99%