Small Bowel Adenocarcinoma Metastatic to the Ovaries in a 12-Year-Old Girl

Abstract

Making an accurate diagnosis of tumors metastatic to the ovary can be difficult and requires attention to histologic detail. Small bowel adenocarcinoma is usually a chemoresistant tumor with extremely poor outcome. This patient had a moderate response to chemotherapy and a prolonged survival compared to that of patients previously reported.

Autotransplantation of cryopreserved ovarian tissue in cancer survivors and the risk of reintroducing malignancy: a systematic review

“…Nevertheless, ovarian involvement has been indicated in case reports describing patients with hepatocellular carcinoma (Oortman and Elliott, 1983;Young et al, 1992a, b;de Groot et al, 2000;Stippel et al, 2005;Montero et al, 2007;Lee et al, 2011;Benito et al, 2012), hepatoblastoma (Green and Silva, 1989) and bile duct or gallbladder carcinomas (Lashgari et al, 1992;Petru et al, 1992;Chang et al, 1997;Ayhan et al, 2001;Low et al, 2003;Miyagui et al, 2003;Garcia et al, 2004;Jain et al, 2006;Khunamornpong et al, 2007Khunamornpong et al, , 2008Lee et al, 2009;Kumar et al, 2010;Singh et al, 2010;Pusiol et al, 2011). Tumours of the small bowel and pancreatic tumours were also shown to have the capacity to metastasize to the ovaries (Roley et al, 1990;Tsuruchi et al, 1995;Loke et al, 1997;Dunsmore and Lovell, 1998;Wysocki et al, 2001;Yanai et al, 2003;Ayhan et al, 2005;Husain et al, 2006;Maekawa et al, 2010).…”

Jejunal Adenocarcinoma: A Rare Cause of Chronic Anemia in Children

“…We describe an adolescent female presenting with chronic anemia and abdominal pain who had a jejunal adenocarcinoma. Only eight cases of jejunal adenocarcinoma have been reported in patients under 20 years of age (2,3).…”

Adenocarcinoma of the small bowel

“…Primary small bowel malignant tumours are rare and constitute 1–3% of all GI tract malignancies and less than 2% of all human malignancies 1–4 . The peak incidence occurs in the sixth and seventh decades of life but small bowel cancer has been described in children as young as 12 years of age 5 . As with colorectal tumours, they are more prevalent in the developed world 6 .…”

“…[1][2][3][4] The peak incidence occurs in the sixth and seventh decades of life but small bowel cancer has been described in children as young as 12 years of age. 5 As with colorectal tumours, they are more prevalent in the developed world. 6 They show a slight male and black predominance [6][7][8] and, although rare (annual incidence <1.4 per 100 000 population 2,8-10 ), the incidence is rising.…”