Objective: Increased waist circumference(WC) and/or BMI are often considered as being risk factors(RF) of metabolic syndrome(MS) and other cardiovascular diseases. Aim is to analyse correlation of WC and BMI with other components of MS, as well as with such RF as age, total cholesterol(TC), LDL-c and CRP. Methods: We analysed correlation of these parameters in 773 outpatients(mean age55.6; 73%women) by using Pearson's correlation coefficient. Results: We found out higher BMI in women than in men(29.22vs.28.37kg/m²; p=0.055), while WC was relatively lower in women compared to men(93.25vs.99.13cm; p<0.0001). There was a positive correlation between WC and age, however, BMI had any correlation with age only in women. Both WC and BMI showed a reliable positive correlation with SBP and DBP. Correlations of WC and BMI with lipids, blood glucose and CRP showed that WC and BMI have a positive significant correlation with TG, glucose and CRP, and a negative correlation with HDL-c. We did not find any correlation of WC and BMI with TC. Only BMI had a positive correlation with LDL-c. Only in women correlation of WC and BMI with LDL-c and CRP could be considered as being reliable. Conclusions: There is a significant correlation of WC and BMI with SBP,DBP,TG, glucose and HDL-c, which indicates close relationship among all components of MS. WC increases with age only in women. In women WC and BMI correlates with LDL-c and CRP, this indicates that women are at higher risk regarding obesity. Funding: This trial has been financed by research Project of Scientific Council of Latvia Ministry of Education and Health 95 95 95 95