Slowly-inactivating potassium conductances in compartmental interneuron models

Dynamics and diversity in interneurons: a model exploration with slowly inactivating potassium currents

“…The robustness of the burst frequency with respect to injected current amounts, is a result of the intricate balance and interplay of the intrinsic currents that make up the signal. This robust output is seen only in the extended multi-compartment model, suggesting that morphology may play an active role in the generation or stabilization of signals (Saraga and Skinner, 2002). Using our multi-compartment model we ¢nd that it is possible to obtain situations where the cell does not ¢re, but produces a steady-state signal regardless of the amount of injected current.…”