Slowly Enlarging, Erythematous Macule in a Child

The Relationship between Angioblastoma (Nakagawa) and Tufted Angioma: Report of Four Cases with Angioblastoma and a Literature‐Based Comparison of the Two Conditions

“…More than 130 cases ofAB have been reported in Japan since Nakagawa (1) reported the first case in 1949. Although AB was originally considered to occur only inJapan, similar cases have been reported under the name TA in Europe and the U.S. (2)(3)(4)(5)(6)(7). TA is an angioma reported by Wilson:Jones in 1976.…”

“…Many other TA cases have been reported in Europe and the U.S. since Wilson:Jones reported his first case, while only eight cases have been reported as "TA" inJapan. Some investigators consider that TA and AB are the same disease (6,7,9,10), while others insist that these two diseases have to be distinguished from each other because their biological activities are different (11,12) and that they are not the same disease clinically or pathologically (13)(14)(15). Therefore, we evaluated 51 cases of AB reported within the last 15 years inJapan, including the four cases we encountered, and 44 accessible cases of TA reported in Europe and the U.S., and compared them.…”

“…Originally, TA was introduced as a class of disease to be differentiated from Kaposi's sarcoma. Wilson:Jones chose the name "tufted angioma (TA)" to avoid confusing "angioblastoma (AB)" with the hemangioblastoma that occures in the cerebellum (6). We think that, if both TA and AB are the same disease, it would be appropriate to use the name "angioblastoma" in respect for the priority of the first report of the disease presented by Nakagawa (1), 27 years earlier than the report by Wilson:Jones.…”