Slow potential shifts following cerebellar stimulation

Dondey, M; Snider, Ray S.

doi:10.1016/0013-4694(55)90039-0

Cited by 18 publications

(2 citation statements)

References 8 publications

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“…The great sensitivity of neurons to small voltage differences tends to support the views already suggested to the effect that electric field actions can play a role in the determination of probability of firing of units in ganglionic masses within the central nervous system,49-56 at least in synchronizing cells,6' 7 -5 and that currents adequate to exert an effect are physiologically available.7' 16,19,[65][66][67][68][69][70][71][72][73][74] If this is true, the considerations adduced here emphasize the significance of the morphology of the cell, since the geometric relations between the portions of the cell or dendritic membrane specially sensitive to the transmembrane changes, or the regions sensitive to difference in potential between different points on the surface with relation to the external field, acquire an overriding importance. Even more, the view here expressed emphasizes the importance of the architectural arrangements of groups of neurons and of their complex dendritic ramifications, which will be, as it were, antennae oriented with respect to the direction of currents of physiological significance to these cell masses.…”

Section: Discussionsupporting

confidence: 66%

Measurement of Imposed Voltage Gradient Adequate to Modulate Neuronal Firing

Terzuolo

Bullock

1956

Proc. Natl. Acad. Sci. U.S.A.

211

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results when the protein intake is 24 per cent is any higher than the level of calcium which gives the best results when the protein intake is 14 per cent. The present studies seem to indicate that the most beneficial level of calcium intake when the protein intake is liberal lies in the range of 0.4-0.6 per cent, or two to three times the level of minimal adequacy. In earlier studies,8 where calcium alone was added to Diet A, the level of optimum intake appeared to be at least three, and perhaps as much as four, times the level of minimal adequacy. Finally, it would seem justifiable to conclude that a diet liberal both in calcium and in protein is clearly superior to a diet liberal only in protein. * This work has been aided by grants to Columbia University, at first from the John and Mary Markle Foundation, more recently from the Nutrition Foundation, Inc., the Williams-Waterman Fund in the Research Corporation, and Swift and Company. t Deceased October 7, 1955. ' A comparison will soon be published of the life-histories of such late-generation Diet A animals with those of their ancestors whose families had been on the diet only about half as many generations and with those of their early forebears whose families had only recently been transferred to the diet.

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