“…Normative values for the corneal endothelium cell density in middle aged adults are >2700 cells/mm 2 , coefficient of variation of 0.27 and a hexagonal cell index >60 % [111] (see also CLEAR Anatomy Report [113]. However, endothelial cell morphology varies regionally, with a greater endothelial cell density and more regular cell shape in the mid-peripheral and peripheral cornea compared to centrally [114,115]. In addition, a limitation of specular microscopy is that the procedure only images one side of an endothelial cell [116].…”