Slipped capital femoral epiphysis associated with hyperparathyroidism

Kinoshita, J.; Kaneda, Kiyoshi; Matsuno, Takeo; Hosokawa, Y.; Nagashio, R.

doi:10.1007/bf00185232

Cited by 21 publications

(10 citation statements)

References 14 publications

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“…From our case and the literature reviewed below. [5][6][7][8][9][10][11][12][13][14][15][16] (Table 2), we found that almost all the cases were reported in later adolescence with an average age of 13.5 years and there was no difference in incidence among males and females.…”

Section: Discussionmentioning

confidence: 93%

Slipped capital femoral epiphysis as primary presentation in an adolescent with primary hyperparathyroidism due to ectopic mediastinal parathyroid adenoma

Badhe,

Patil,

Vikram Reddy

et al. 2023

Clinical Case Reports

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Section: Discussionmentioning

confidence: 93%

Slipped capital femoral epiphysis as primary presentation in an adolescent with primary hyperparathyroidism due to ectopic mediastinal parathyroid adenoma

Badhe,

Patil,

Vikram Reddy

et al. 2023

Clinical Case Reports

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“…Parathyroid adenoma is the predominant cause of primary hyperparathyroidism. When considering intervention, Kinoshita et al recommended surgical excision of the parathyroid adenoma prior to orthopaedic intervention since a low-grade slip may resolve with correction of the metabolic disturbance 23 . However, subsequent authors have provided a treatment algorithm for treatment priority in patients with SCFE based on the severity of hypercalcemia: severe hypercalcemia, defined as total serum calcium of >14 mg/dL (3.5 mmol/L), requires urgent parathyroidectomy, whereas mild or moderate serum calcium levels allow for a staged or combined treatment approach 24 .…”

Section: Endocrinopathies Associated With Scfementioning

confidence: 99%

Slipped Capital Femoral Epiphysis Associated with Endocrinopathy

et al. 2022

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Slipped capital femoral epiphysis (SCFE) has a well-documented association with underlying endocrine conditions, including thyroid hormone aberrations and parathyroid dysfunction.Recombinant growth hormone therapy has also been identified as a risk factor for the development of SCFE.Presentation before their 10th birthday or after their 16th birthday along with height of <10th percentile are reliable risk factors for identifying children with an SCFE who are at a heightened risk for an underlying endocrinopathy and can been used to guide selective laboratory testing.Patients with unilateral SCFE presentations with an underlying endocrinopathy are at a heightened risk for contralateral slip development and should be treated with prophylactic fixation.

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“…Possible sequelae of SCFE include avascular necrosis, chondrolysis, leg length discrepancy (LLD), and early degenerative joint disease [2,3]. Obesity, endocrine, and systemic disorders are known to be associated with an increased incidence of SCFE [4][5][6][7]. When combined with increased body weight and retroversion of the femoral head, the loads may exceed the ultimate yield point, causing a shift in position of the epiphysis in relation to the metaphysis of the femoral head.…”

Section: Introductionmentioning

confidence: 99%

Epidemiology and demographics of slipped capital femoral epiphysis in South Korea: A nationwide cohort study

Kim

Min

et al. 2023

PLoS ONE

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Background This study investigated the epidemiology and demographics of slipped capital femoral epiphysis (SCFE) in South Korea using a nationwide population-based database. Methods Information on sex, age at onset, endocrine comorbidities, history of growth hormone therapy, history of radiation therapy, surgical methods, and complications in patients with SCFE aged younger than 18 years between 2007 and 2019 was retrieved from the Korean Health Insurance Review and Assessment Service database. Results Data were available for 586 children (429 boys, 157 girls). The average age at onset was 11.1 ± 1.8 years (boys, 11.3 ± 1.9; girls, 10.6 ± 1.5). Five hundred and twenty-nine (90.3%) patients were aged 9–14 years; the incidence rate in this age group was 6.0/100,000 (95% confidence interval, 5.5–6.6) and significantly higher in boys (8.4 vs 3.5, p<0.001). There was a significant increase in the annual incidence rate from 0.96/100,000 in 2009 to 2.05/100,000 in 2019 (p = 0.006). Ninety-five patients (16.2%) had endocrine comorbidities or a history of hormone/radiation therapy. Osteotomy and internal fixation were performed in 59 patients and in situ pinning in 527. Seventy-six patients developed postoperative complications. Conclusion The annual incidence rate of SCFE in South Korea has increased since 2009.

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Slipped capital femoral epiphysis associated with hyperparathyroidism

Cited by 21 publications

References 14 publications

Slipped capital femoral epiphysis as primary presentation in an adolescent with primary hyperparathyroidism due to ectopic mediastinal parathyroid adenoma

Slipped capital femoral epiphysis as primary presentation in an adolescent with primary hyperparathyroidism due to ectopic mediastinal parathyroid adenoma

Slipped Capital Femoral Epiphysis Associated with Endocrinopathy

Epidemiology and demographics of slipped capital femoral epiphysis in South Korea: A nationwide cohort study

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