2020
DOI: 10.3390/tropicalmed5020057
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Sleeping Sickness at the Crossroads

Abstract: Human African trypanosomiasis (HAT; sleeping sickness) is a disease with truly historic dimensions [...]

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Cited by 8 publications
(7 citation statements)
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“…Bei klinisch schweren Formen wird immer noch eine Lumbalpunktion durchgeführt und bei pathologischem Liquor die Kombinationstherapie Nifurtimox per os / Eflorni thin intravenös angewendet [2]. Die perorale Behandlung kann nun auch in nicht optimal eingerichteten Gesundheits zentren in der Peripherie durchgeführt werden [3]. Durch diese Anstrengungen gingen die Schlafkrankheitsfälle wieder deut lich zurück.…”
Section: Die Krankheitunclassified
“…Bei klinisch schweren Formen wird immer noch eine Lumbalpunktion durchgeführt und bei pathologischem Liquor die Kombinationstherapie Nifurtimox per os / Eflorni thin intravenös angewendet [2]. Die perorale Behandlung kann nun auch in nicht optimal eingerichteten Gesundheits zentren in der Peripherie durchgeführt werden [3]. Durch diese Anstrengungen gingen die Schlafkrankheitsfälle wieder deut lich zurück.…”
Section: Die Krankheitunclassified
“…However, a similar situation was already achieved in the 1960s, which was followed by a reduction in surveillance and control activities and as a consequence the disease resurfaced again in the 1990s (Brun et al, 2010). This advocates that efforts to develop trypanosomespecific diagnostics and therapeutics should not be suspended (Burri, 2020). Five drugs are currently used in the treatment of HAT (Büscher et al, 2017).…”
Section: Introductionmentioning
confidence: 96%
“…However, a similar situation was already achieved in the 1960s, which was followed by a reduction in surveillance and control activities and as a consequence the disease resurfaced again in the 1990s ( 3 ). This advocates that efforts to develop trypanosome-specific diagnostics and therapeutics should not be suspended ( 4 ). Five drugs are currently used in the treatment of HAT ( 5 ).…”
Section: Introductionmentioning
confidence: 99%