Sleep spindle density and temporal clustering are associated with sleep-dependent memory consolidation in Parkinson’s disease
Soraya Lahlou,
Marta Kaminska,
Julien Doyon
et al.
Abstract:Sleep is required for successful memory consolidation. Sleep spindles, bursts of oscillatory activity occurring during non-REM sleep, are known to be crucial for this process and, recently, it has been proposed that the temporal organization of spindles into clusters might additionally play a role in memory consolidation. In Parkinson's disease, spindle activity is reduced, and this reduction has been found to be predictive of cognitive decline. However, it remains unknown whether alterations in sleep spindles… Show more
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