Sleep-related rhythm in 6 cpm power of electrogastrogram during sleep in constipated young women

Abstract

The purpose is to investigate the 90-min sleep-related rhythm of intestinal motility in constipated women by spectral analysis of electrogastrograms (EGG). Constipation is classified into two types, spastic and flaccid. The study was performed on 51 subjects who slept for 300 min. We evaluated the amplitude of 90-min cycle and maximal time (lag-time) of the 6 cpm (cycles per minute) power on the EGG by cosinor analysis. We introduced a power analysis by calculating the sample effect size and statistical power. The 6 cpm power increased at the beginning of the time span in flaccid and non-constipation groups, but not in the spastic group. The amplitude of the 90-min cycle showed a significant difference between flaccid and non-constipation groups, but no difference between spastic and flaccid groups. We conclude that the 6 cpm power is affected by parasympathetic activity during sleep and the sleep-related rhythm of the power is higher in constipated subjects.