Sleep quality in rheumatoid arthritis, and its association with disease activity in a Korean population

Son, Chang-Nam; Choi, Go; Lee, So‐Yeon; Lee, Ji-Min; Lee, Tae Han; Jeong, Hye-­Jin; Jung, Chang-Gyu; Kim, Jimin; Cho, Yong Won; Kim, Sang-Hyon

doi:10.3904/kjim.2015.30.3.384

Cited by 50 publications

(47 citation statements)

References 23 publications

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“…Our study has shown poor-sleep patients had significantly higher levels of disease activity compared with good-sleep patients. Importantly, logistic regression analysis indicated that disease activity is a major contributor to sleep quality, which is consistent with previous studies from Turkey and Korea [4, 27]. Additionally, the ESR was found to be associated with sleep quality in our study, which was in line with prior research reports [4].…”

Section: Discussionsupporting

confidence: 93%

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Sleep quality in Chinese patients with rheumatoid arthritis: contributing factors and effects on health-related quality of life

Guo

Yin

et al. 2016

Health Qual Life Outcomes

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BackgroundPoor sleep quality is common in rheumatoid arthritis (RA) patients and may lead to disease aggravation and decreased health-related quality of life (HRQoL). The increasing prevalence of poor sleep in RA patients is associated with adverse demographic, clinical, and psychological characteristics. However, there are currently no known reported studies related to the effects of sleep quality on HRQoL in RA patients from China. This cross-sectional study aims to evaluate the contributors of poor sleep and the effects of sleep quality on HRQoL in Chinese RA patients.MethodsA self-report survey was administered to 131 RA patients and 104 healthy individuals using the Pittsburgh Sleep Quality Index (PSQI) for sleep quality. RA patients completed the Hospital Anxiety and Depression Scale for anxiety and depression, the 28-joint Disease Activity Score for disease activity, the 10 cm Visual Analog Scale for pain, the Health Assessment Questionnaire-Disability Index for functional capacity and the Short Form 36 health survey for HRQoL. Blood samples were taken to gain some biochemical indicators (e.g., erythrocyte sedimentation rate, C-reactive protein, rheumatoid factor, and anti-cyclic citrullinated peptide). Independent samples t-tests, Chi square analysis, logistic regression modeling and linear regression were used to analyze these data.ResultsOur results found that the prevalence of poor sleep (PSQI ≥ 5) was 78.6% and the mean global score of PSQI was 7.93 (SD 3.98) in patients, which were significantly higher than the controls (18.7% and 3.88 (SD 1.89), respectively). There were significant correlations among synthetic disease-modifying antirheumatic drugs, erythrocyte sedimentation rate, pain, disease activity, functional capacity, anxiety/depression and sleep quality in RA patients. Meanwhile, logistic regression models identified disease activity and depression as predictors of poor sleep quality. Poor RA sleepers had impaired HRQoL than good RA sleepers, and sleep quality was independently and significantly associated with social function and mental components summary.ConclusionsThe majority of Chinese RA patients suffered from poor sleep, which significantly impairs their HRQoL. The data suggested the need for holistic assessment and management of RA patients and the importance of objective interventions to improve their sleep quality and finally to improve their HRQoL.Electronic supplementary materialThe online version of this article (doi:10.1186/s12955-016-0550-3) contains supplementary material, which is available to authorized users.

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Section: Discussionsupporting

confidence: 93%

“…It has been reported that several factors of demographic, clinical and psychogenic variables have an influence on sleep quality [27–29]. In our study, patients with a PSQI score ≥5 were found to have significantly more frequently use synthetic DMARDs.…”

Section: Discussionsupporting

confidence: 51%

Sleep quality in Chinese patients with rheumatoid arthritis: contributing factors and effects on health-related quality of life

Guo

Yin

et al. 2016

Health Qual Life Outcomes

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“…Previous studies used the PSQI as a sleep instrument tool for patients with RA, along with use of confirmatory factor analysis. 5,32,35 The JSS-TR had a moderate to strong correlation with most of the subsets of the NHP and the PSQI. The strongest one was with the NHP emotional reactions and pain subsets.…”

Section: Discussionmentioning

confidence: 98%

The Validity and Reliability of Turkish Version of the Jenkins Sleep Evaluation Scale in Rheumatoid Arthritis

et al. 2018

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“…Previous case-control studies in this regard with healthy controls have reported similar results. 3,20 Sleep disturbances in RA tend to be multifactorial. Beyond pain, there appears to be a complex and dynamic interplay between the clinical aspects of RA and sleep quality.…”

Section: Discussionmentioning

confidence: 99%

Anti-Citrullinated Cyclic Peptide Antibody and Functional Disability Are Associated With Poor Sleep Quality in Rheumatoid Arthritis

Rajalingam¹,

Sakthiswary

Hussein³

2017

Arch Rheumatol

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Objectives: This study aims to determine the predictors of poor sleep quality in rheumatoid arthritis (RA). Patients and methods:This was a monocentric, cross sectional, case-control study which was conducted at the Putrajaya Hospital, Malaysia. We recruited 46 patients with RA (3 males; 43 females; mean age 48.15±14.96) and 46 age and sex-matched healthy controls (3 males; 43 females; mean age 47.11±12.22). RA patients were assessed for their disease activity based on disease activity score in 28 joints, disease damage based on radiographic erosions, and functional status based on Health Assessment Questionnaire Disability Index. The Pittsburgh Sleep Quality Index (PSQI) scores were determined by interviewing all the subjects. Subjects with RA were further subdivided based on their PSQI scores as "good sleepers" with PSQI scores of <5 and "poor sleepers" with PSQI scores of ≥5. Results: The percentage of poor sleepers was significantly higher among RA patients (47.83% vs 9.57%). Median scores of 5 out of 7 components of the PSQI were higher among RA patients compared to controls. Among poor sleepers with RA, a significantly higher proportion tested positive for anti-citrullinated cyclic peptide autoantibodies (p=0.037). Besides, poor sleepers had significantly higher median Health Assessment Questionnaire Disability Index (p=0.017) than good sleepers. However, both Health Assessment Questionnaire Disability Index (p=0.968) and anti-citrullinated cyclic peptide (p=0.431) were insignificant when entered in the equation of a logistic regression model. Conclusion:The findings of this study demonstrate a link between functional disability, anti-citrullinated cyclic peptide antibodies, and sleep quality in RA.

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Sleep quality in rheumatoid arthritis, and its association with disease activity in a Korean population

Cited by 50 publications

References 23 publications

Sleep quality in Chinese patients with rheumatoid arthritis: contributing factors and effects on health-related quality of life

Sleep quality in Chinese patients with rheumatoid arthritis: contributing factors and effects on health-related quality of life

The Validity and Reliability of Turkish Version of the Jenkins Sleep Evaluation Scale in Rheumatoid Arthritis

Anti-Citrullinated Cyclic Peptide Antibody and Functional Disability Are Associated With Poor Sleep Quality in Rheumatoid Arthritis

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