Sleep quality in patients with xerostomia: a prospective and randomized case-control study

Jornet, Pía López; Berdugo, Maira Lucero; Fernandez-Pujante, Alba; C, Castillo Felipe; C, Zamora Lavella; Pons-Fuster, Alvaro; J, Silvestre Rangil; Silvestre, Francisco-Javier

doi:10.3109/00016357.2015.1099730

Cited by 18 publications

(14 citation statements)

References 27 publications

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“…In this sample we have previously reported a significant increased risk for xerostomia and sleep disturbances among the CA group [3]. Sleep disturbances related to xerostomia have been mentioned in different medical condition [40][41][42][43]. Sleep disturbances in relation to caries activity must be considered unique and the relationship to general health needs more research.…”

Section: Discussionmentioning

confidence: 90%

Self-reported oral and general health related to xerostomia, hyposalivation, and quality of life among caries active younger adults

Flink

Tegelberg

Arnetz

et al. 2019

Acta Odontologica Scandinavica

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Objective: The aim was to study prevalence of xerostomia, hyposalivation and quality of life among caries active younger adults. Materials and methods: A questionnaire regarding oral and general health, xerostomia and quality of life was mailed to 134 caries active (CA) and 40 caries inactive (CI) patients, 25-50 years of age (mean age 39.9 ± 6.2 years) treated at a Swedish Public Dental Service clinic, regarding oral and general health, xerostomia and quality of life. Caries data and unstimulated whole salivary flow rates were obtained from dental records. Results: The overall response rate was 69%. Dental records confirmed that CA patients had more decayed teeth over time than CI patients (p < .001). The CA group reported worse oral health (p < .001) and general health (p < .01), more xerostomia (p < .001) and lower salivary flow rate (p < .01) compared to CI patients. Xerostomia was inversely related to unstimulated whole salivary flow rates as well as to oral and general health (p < .01). There were no differences between groups in quality of life. Conclusion: Younger caries active adult patients reported significantly more xerostomia and hyposalivation compared to caries inactive patients. Xerostomia and hyposalivation were inversely related to perceptions of oral and general health, but not to quality of life.

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Section: Discussionmentioning

confidence: 90%

Self-reported oral and general health related to xerostomia, hyposalivation, and quality of life among caries active younger adults

Flink

Tegelberg

Arnetz

et al. 2019

Acta Odontologica Scandinavica

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“…Hyposalivation as well as xerostomia, may also affect other oral functions such as chewing, swallowing and denture wearing and may also increase the risk for both dental caries and erosion . In 50‐ to 75‐year‐old subjects other oral symptoms like burning mouth, difficulties in opening the mouth and gum bleeding as well as intake of medications and the habit of smoking have been shown to be related to xerostomia, especially during the night …”

Section: Introductionmentioning

confidence: 99%

Self‐reported dry mouth in 50‐ to 80‐year‐old Swedes: Longitudinal and cross‐sectional population studies

Johansson

Unell

Ekbäck

et al. 2019

J of Oral Rehabilitation

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Xerostomia is a common condition among elderly. The objectives were to examine prevalence, persistence, progression, yearly incidence of xerostomia, associated background factors and its influence on oral impacts on daily performances (OIDP) in 50‐ to 80‐year‐old people. In 1992, a questionnaire was sent to all 50‐year‐old (n = 8888) and in 2007 to all 75‐year‐old persons (n = 5195) living in two Swedish counties. In 2012, the same questionnaire was sent to both age cohorts, now 70‐ and 80‐year‐old. Response rate was for the 50‐, 70‐ 75‐ and 80‐year‐old groups 71.4%, 72.2%, 71.9% and 66.4%, respectively. In the 50‐ to 70‐year‐old sample, 40.3% of the participants answered all five examinations and in the 75‐80 group 49.5% (intact samples). In all age groups, xerostomia was significantly more prevalent in women than in men. At age 80, “often mouth dryness at night” was reported by 24.3% and 16.2% of women and men, respectively. Prevalence increased with age and was more frequent at night‐time. Persistence of xerostomia was reported by 61.4%‐77.5%, progression by 11.5%‐33.0% and remission by 5.7%‐11.3%. Average yearly incidence was 0.99%‐3.28%. Xerostomia was more prevalent in those who reported a negative impact on OIDP. Highest odd ratios for xerostomia were burning mouth (OR 12.0), not feeling healthy (OR 5.1) and medicine usage (OR 3.9). Xerostomia is common in older age, persistence is high and progression common. The comorbidity between xerostomia, oral health problems and impaired general health needs to be taken into consideration when providing dental care to elderly patients.

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“…Another important finding is that the biggest effect and score difference were obtained in the malic acid lozenge group for the psychological discomfort dimension of the OHIP‐14‐PT. This is noteworthy because it has been suggested that patients with xerostomia experience an increased prevalence of anxiety and depression (Lopez ‐Jornet et al, ). In the malic acid lozenge group, the difference was nearly twice the MID, suggesting that the GSSS from this group provide considerable improvement in this dimension.…”

Section: Discussionmentioning

confidence: 94%

Patient‐related outcomes in Sjögren syndrome treated with stimulants of salivary secretion: Randomized clinical trial

et al. 2019

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Objectives To investigate the impact of gustatory stimulants of salivary secretion (GSSS) on Sjögren's syndrome patients’ self‐perception of xerostomia, oral health‐related quality of life (OHRQoL) and salivary secretion. Methods A total of 110 Sjögren's syndrome patients were randomly allocated to be treated with either a malic acid lozenge or a citric acid mouthwash and then crossed over. Before and after the interventions, the Xerostomia Inventory 5 (SXI‐5‐PL) and the Oral Health Impact Profile (OHIP‐14‐PT) questionnaires (both in the Portuguese language) were administered to patients. Unstimulated, mechanical and gustatory‐stimulated salivary flows were determined. Repeated measures and between‐subject analyses were performed. Statistical significance was set at 5%. Results After the intervention and within each group, both GSSS elicited a reduction in the SXI‐5‐PL and OHIP‐14‐PT scores and an increase in salivary output, significant in the malic acid lozenge group. The malic acid treatment resulted in a greater effect size and percentage improvement than citric acid mouthwash. The malic acid lozenge also produced a significant greater salivary output than the citric acid rising solution. Conclusions In Sjögren's syndrome patients, lozenges containing malic acid increased saliva production and xerostomia relief, resulting in improved quality of life.

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Sleep quality in patients with xerostomia: a prospective and randomized case-control study

Cited by 18 publications

References 27 publications

Self-reported oral and general health related to xerostomia, hyposalivation, and quality of life among caries active younger adults

Self-reported oral and general health related to xerostomia, hyposalivation, and quality of life among caries active younger adults

Self‐reported dry mouth in 50‐ to 80‐year‐old Swedes: Longitudinal and cross‐sectional population studies

Patient‐related outcomes in Sjögren syndrome treated with stimulants of salivary secretion: Randomized clinical trial

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