Sleep quality and quality of life in patients with moderate to very severe chronic obstructive pulmonary disease

Kim

et al. 2020

Clinical Respiratory J

Introduction Poor sleep quality in patients with chronic obstructive pulmonary disease (COPD) has been associated with poor health outcomes. However, there is a lack of research on factors associated with sleep disturbance in patients with COPD. Objectives We investigated patterns of sleep disturbance and factors associated with sleep impairment in patients with COPD. Methods This was a prospective, multicenter cross‐sectional study enrolling a sample of 245 COPD subjects. All patients completed the patient‐reported measure, the COPD and Asthma Sleep Impact Scale (CASIS) to assess sleep impairment. The St. George’s Respiratory Questionnaire (SGRQ), the 36‐item Short‐Form health survey (SF‐36), Hospital Anxiety and Depression Scale (HADS), and the COPD Self‐Efficacy Scale (CSES) were utilized to assess health‐related quality of life (HRQL), anxiety/depression and self‐efficacy, respectively. Results About 35.1% of the patients reported that they had a bad night’s sleep. Univariate analysis showed that the CASIS total score was significantly correlated with the modified Medical Research Council dyspnea scale, SGRQ total score, SF‐36 PCS, SF‐36 MCS, HADS‐A, HADS‐D and CSES (all P < 0.05). In a multivariate analysis, SGRQ total (r = 0.19, P = 0.006), SF‐36 PCS (r = 0.14, P = 0.037), HADS‐D (r = 0.24, P ≤ 0.001), and CSES(r = −0.12, P = 0.010) were independently associated with the CASIS score. Conclusions In this study, 35% of clinically stable patients with COPD reported poor sleep quality. Depression, poorer HRQL and self‐efficacy were significantly associated with sleep disturbance in patients with COPD.

Section: Discussionmentioning

confidence: 99%

Factors associated with sleep disturbance in patients with chronic obstructive pulmonary disease

Kim

et al. 2020

Clinical Respiratory J

“…Previous studies have reported sleep problems in patients with COPD using COPD‐specific and non‐COPD‐specific measures. The majority of sleep studies in COPD have relied on two non‐disease‐specific measures, that is, the Pittsburgh Sleep Quality Index and/or the Epworth Sleep Scale . These generic measures, which cover broadly defined domains such as functional status and perceptions, may not perform well in patients with COPD considering no data of reliability or validity tests to justify their use in this population .…”

Section: Discussionmentioning

confidence: 99%

Sleep disturbance in patients with mild‐moderate chronic obstructive pulmonary disease

Kim

et al. 2019

Clinical Respiratory J

Introduction Although sleep problems have an important impact on daily life and health outcome measures in patients with chronic obstructive pulmonary disease (COPD), patterns of sleep disturbance in patients with mild‐moderate COPD remain unknown. Objective The aim of this study was to investigate patterns of sleep disturbance and factors associated with sleep impairment in patients with mild‐moderate COPD. Methods This prospective cross‐sectional study enrolled 148 male patients with COPD. At enrolment, all patients completed a disease‐specific sleep measure, the COPD and Asthma Sleep Impact Scale (CASIS) to assess sleep impairment. Health‐related quality of life (HRQL) was measured using the St. George's Respiratory Questionnaire (SGRQ) and the 36‐item Short‐Form health survey (SF‐36). Anxiety and depression status were assessed using the Hospital Anxiety and Depression Scale (HADS). Self‐efficacy was measured by the COPD Self‐Efficacy Scale (CSES). Results The mean age of the subjects was 67 years [standard deviation (SD) = 8.11]. The proportion of patients who indicated that they had a bad night's sleep was 33.1%. Univariated analysis showed that CASIS score was significantly correlated with the modified Medical Research Council (mMRC) dyspnea scale, SGRQ, SF‐36 Physical Component Summary, SF‐36 Mental Component Summary, HADS‐anxiety, HADS‐depression and CSES scores (all P < 0.05). In a multivariate analysis, SGRQ and CSES were independently associated with CASIS score. Conclusion Poorer HRQL and lower self‐efficacy are significantly associated with sleep disturbance and perhaps may be improved by better sleep quality. Future research is required to enhance sleep quality in patients with mild‐moderate COPD.

“…However, it is not correct to conclude that the improvement in gas exchange is responsible for all of the clinically relevant improvements achieved, as the relationship between gas exchange parameters and HRQoL for example is very limited. Effects such as improvement in sleep quality and sputum clearance, and a reduction in exacerbation rate probably all act positively on HRQoL [ 40 , 65 , 66 ].…”

Section: Challenges In Noninvasive Ventilationmentioning

confidence: 99%

Noninvasive ventilation in stable hypercapnic COPD: what is the evidence?

Duiverman

2018

ERJ Open Res

Long-term noninvasive ventilation (NIV) to treat chronic hypercapnic respiratory failure is still controversial in severe chronic obstructive pulmonary disease (COPD) patients. However, with the introduction of high-intensity NIV, important benefits from this therapy have also been shown in COPD. In this review, the focus will be on the arguments for long-term NIV at home in patients with COPD. The rise of (high-intensity) NIV in COPD and the randomised controlled trials showing positive effects with this mode of ventilation will be discussed. Finally, the challenges that might be encountered (both in clinical practice and in research) in further optimising this therapy, monitoring and following patients, and selecting the patients who might benefit most will be reviewed.