Sleep quality and cognitive function in healthy old age: The moderating role of subclinical depression.

Sutter, Christine; Zöllig, Jacqueline; Allemand, Mathias; Martin, Mike

doi:10.1037/a0030033

Cited by 60 publications

(41 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The current study found no association between memory and subjective sleep quality or quantity, which is consistent with some (Sutter et al, 2012), but not other research (Miller et al, 2014;Schmutte et al, 2007). Previous studies are likely to have included people with sleep disorders (Miller et al, 2014;Schmutte et al, 2007;Waller et al, 2015), such as sleep apnoea, which is independently associated with memory impairment (Wallace and Bucks, 2013), and may account for some of the associations previously reported between subjective sleep measures and memory performance.…”

Section: Discussionsupporting

confidence: 88%

“…Research on habitual sleep patterns and memory in older adults has also been conducted using subjective measures of sleep; however, the area is again marked by significant inconsistencies in outcomes. Self-reported sleep quality, with the exception of sleep-onset latency (SOL; time taken to fall asleep), has not generally been associated with poor memory in older adults, after controlling for depression (Gamaldo et al, 2008;Jaussent et al, 2012;Nebes et al, 2009;Schmutte et al, 2007;Sutter et al, 2012;Tworoger et al, 2006;Waller et al, 2015). However, there are exceptions (Miller et al, 2014); and others have found self-reported poor sleep quality at age 70 years (but not age 50 years) to be associated with greater lifetime risk of developing dementia, in particular Alzheimer's disease (Benedict et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Objective but not subjective sleep predicts memory in community‐dwelling older adults

Cavuoto

Ong

Pike

et al. 2016

Journal of Sleep Research

View full text Add to dashboard Cite

SUMMARYResearch on the relationship between habitual sleep patterns and memory performance in older adults is limited. No previous study has used objective and subjective memory measures in a large, older-aged sample to examine the association between sleep and various domains of memory. The aim of this study was to examine the association between objective and subjective measures of sleep with memory performance in older adults, controlling for the effects of potential confounds. Onehundred and seventy-three community-dwelling older adults aged 65-89 years in Victoria, Australia completed the study. Objective sleep quality and length were ascertained using the Actiwatch 2 Mini-Mitter, while subjective sleep was measured using the Pittsburgh Sleep Quality Index. Memory was indexed by tests of retrospective memory (Hopkins Verbal Learning Test -Revised), working memory (n-back, 2-back accuracy) and prospective memory (a habitual button pressing task). Compared with normative data, overall performance on retrospective memory function was within the average range. Hierarchical regression was used to determine whether objective or subjective measures of sleep predicted memory performances after controlling for demographics, health and mood. After controlling for confounds, actigraphic sleep indices (greater wake after sleep onset, longer sleep-onset latency and longer total sleep time) predicted poorer retrospective (ΔR 2 = 0.05, P = 0.016) and working memory (ΔR 2 = 0.05, P = 0.047). In contrast, subjective sleep indices did not significantly predict memory performances. In community-based older adults, objectively-measured, habitual sleep indices predict poorer memory performances. It will be important to follow the sample longitudinally to determine trajectories of change over time. IN TROD UCTI ONReductions in the length and quality of sleep are common in normal ageing (Ohayon et al., 2004), and while recent research has evaluated the importance of sleep for general cognition (Yaffe et al., 2007) and memory consolidation postlearning (see Scullin and Bliwise, 2015 for comprehensive review), the relationship between habitual sleep patterns and memory in older adults has not been sufficiently studied (Cochrane et al., 2012;Naismith et al., 2011;Seelye et al., 2015;Wilckens et al., 2014). Deterioration in various domains of memory is common with age, and evaluating the relationship between habitual sleep patterns and domains of memory (such as retrospective memory, working memory and prospective memory) will contribute to strategies for improving cognitive health in ageing populations.In studies using polysomnography, which examines cerebral sleep-wake states in addition to other physiological changes that occur with sleep, and is the gold standard of objective sleep measurement, indices of good sleep quality have been associated with better subsequent memory performance (Lafortune et al

show abstract

Section: Discussionsupporting

confidence: 88%

Section: Introductionmentioning

confidence: 99%

Objective but not subjective sleep predicts memory in community‐dwelling older adults

Cavuoto

Ong

Pike

et al. 2016

Journal of Sleep Research

View full text Add to dashboard Cite

show abstract

“…As we expected, the patients with CID alone performed better on the memory task compared to the CDD patients, who performed the worst of the three groups in all five measures of memory. Previous studies have suggested that depression is predictive of poor cognitive ability, even in those suffering from subclinical depression (Sutter, Zollig, Allemand, & Martin, ; Waldron‐Perrine et al, ). In the current study, the CID patients with slight to moderate depressive symptoms performed better on the memory assessments compared to the CDD patients who had concurrent major depressive disorder.…”

Section: Discussionmentioning

confidence: 98%

Patients with chronic insomnia have selective impairments in memory that are modulated by cortisol

et al. 2016

View full text Add to dashboard Cite

Memory impairment is a frequent complaint in insomniacs; however, it is not consistently demonstrated. It is unknown whether memory impairment in insomniacs involves neuroendocrine dysfunction. The participants in this study were selected from the clinical setting and included 21 patients with chronic insomnia disorder (CID), 25 patients with insomnia and comorbid depressive disorder (CDD), and 20 control participants without insomnia. We evaluated spatial working and reference memory, object working and reference memory, and object recognition memory using the Nine Box Maze Test. We also evaluated serum neuroendocrine hormone levels. Compared to the controls, the CID patients made significantly more errors in spatial working and object recognition memory (p < .05), whereas the CDD patients performed poorly in all the assessed memory types (p < .05). In addition, the CID patients had higher levels (mean difference [95% CI]) of corticotrophin-releasing hormone, cortisol (31.98 [23.97, 39.98] μg/l), total triiodothyronine (667.58 [505.71, 829.45] μg/l), and total thyroxine (41.49 [33.23, 49.74] μg/l) (p < .05), and lower levels of thyrotropin-releasing hormone (-35.93 [-38.83, -33.02] ng/l), gonadotropin-releasing hormone (-4.50 [-5.02, -3.98] ng/l) (p < .05), and adrenocorticotropic hormone compared to the CDD patients. After controlling for confounding variables, the partial correlation analysis revealed that the levels of cortisol positively correlated with the errors in object working memory (r = .534, p = .033) and negatively correlated with the errors in object recognition memory (r = -.659, p = .006) in the CID patients. The results suggest that the CID patients had selective memory impairment, which may be mediated by increased cortisol levels.

show abstract

“…Or, it may be that sleep fragmentation and sleep disturbance increase depressive symptoms (Maglione et al ., 2014), which could then influence the rate of cognitive decline. It has been found that poor sleep quality is most strongly associated with cognition, particularly in subclinical depressed older adults (Sutter et al ., 2012). Further research examining whether depression has a mediating role in the association between daytime somnolence and speed of processing may shed light on this particular issue.…”

Section: Discussionmentioning

confidence: 99%

Daytime somnolence as an early sign of cognitive decline in a community‐based study of older people

Tsapanou

O’Shea

et al. 2015

Int J Geriat Psychiatry

View full text Add to dashboard Cite

Objective This study aimed to examine the association between self-reported sleep problems and cognitive decline in community-dwelling older people. We hypothesized that daytime somnolence predicts subsequent cognitive decline. Methods This is a longitudinal study in a 3.2-year follow-up, with 18-month intervals. The setting is the Washington Heights-Inwood Community Aging Project. There were 1098 participants, who were over 65 years old and recruited from the community. Sleep problems were estimated using five sleep categories derived from the RAND Medical Outcome Study Sleep Scale: sleep disturbance, snoring, awaken short of breath/with a headache, sleep adequacy, and daytime somnolence. Four distinct cognitive composite scores were calculated: memory, language, speed of processing, and executive functioning. We used generalized estimating equations analyses with cognitive scores as the outcome, and time, sleep categories and their interactions as the main predictors. Models were initially unadjusted and then adjusted for age, gender, education, ethnicity, depression, and apolipoprotein E-ε4 genotype. Results Increased daytime somnolence (including feeling drowsy/sleepy, having trouble staying awake, and taking naps during the day) was linked to slower speed of processing both cross-sectionally (B = −0.143, p = 0.047) and longitudinally (B = −0.003, p = 0.027). After excluding the demented participants at baseline, the results remained significant (B = −0.003, p = 0.021). Conclusions Our findings suggest that daytime somnolence may be an early sign of cognitive decline in the older population. Copyright # 2015 John Wiley & Sons, Ltd.

show abstract

Sleep quality and cognitive function in healthy old age: The moderating role of subclinical depression.

Cited by 60 publications

References 49 publications

Objective but not subjective sleep predicts memory in community‐dwelling older adults

Objective but not subjective sleep predicts memory in community‐dwelling older adults

Patients with chronic insomnia have selective impairments in memory that are modulated by cortisol

Daytime somnolence as an early sign of cognitive decline in a community‐based study of older people

Contact Info

Product

Resources

About