Sleep Patterns and Stability in Perimenopausal Women

Shaver, Joan; Giblin, Elizabeth C.; Lentz, Martha J.; Lee, Kathryn

doi:10.1093/sleep/11.6.556

Cited by 171 publications

(88 citation statements)

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“…A general consensus drawn from numerous large studies is that the perception of poor and disrupted sleep increases during perimenopause [96 -100]. Yet, objective measures of sleep do not reflect this worsening of sleep quality [101][102][103]. An understanding of the discordance between subjective sleep complaints and objectively measured sleep in peri-and postmenopausal women remains a significant gap in our knowledge.…”

Section: (C) Sex Steroids Influence Sleepmentioning

confidence: 99%

Sex differences in sleep: impact of biological sex and sex steroids

Mong

Cusmano

2016

Phil. Trans. R. Soc. B

367

300

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One contribution of 16 to a theme issue 'Multifaceted origins of sex differences in the brain'. Men and women sleep differently. While much is known about the mechanisms that drive sleep, the reason for these sex differences in sleep behaviour is unknown and understudied. Historically, women and female animals are underrepresented in studies of sleep and its disorders. Nevertheless, there is a growing recognition of sex disparities in sleep and rhythm disorders. Women typically report poorer quality and more disrupted sleep across various stages of life. Findings from clinical and basic research studies strongly implicate a role for sex steroids in sleep modulation. Understanding how neuroendocrine mediators and sex differences influence sleep is central to advancing our understanding of sleep-related disorders. The investigation into sex differences and sex steroid modulation of sleep is in its infancy. Identifying the mechanisms underlying sex and gender differences in sleep will provide valuable insights leading to tailored therapeutics that benefit each sex. The goal of this review is to discuss our current understanding of how biological sex and sex steroids influence sleep behaviour from both the clinical and pre-clinical perspective.

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Section: (C) Sex Steroids Influence Sleepmentioning

confidence: 99%

Sex differences in sleep: impact of biological sex and sex steroids

Mong

Cusmano

2016

Phil. Trans. R. Soc. B

367

300

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“…Three of the studies found no differences in sleep architecture based on menopausal state. [7][8][9] In a large epidemiological study, sleep architecture was better in perimenopausal and postmenopausal women compared to premenopausal women. 6 One study in patients with insomnia found worsening sleep architecture in peri-and postmenopausal women compared to premenopausal women.…”

Section: Introductionmentioning

confidence: 99%

Sleep During Menopausal Transition: A 6-Year Follow-Up

Lampio¹,

Polo‐Kantola²,

Himanen³

et al. 2017

Sleep

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Study Objectives: Menopausal transition is associated with increased dissatisfaction with sleep, but the effects on sleep architecture are conflicting. This prospective 6-year follow-up study was designed to evaluate the changes in sleep stages and sleep continuity that occur in women during menopausal transition. Methods: Sixty women (mean age 46.0 years, SD 0.9) participated. All women were premenopausal at baseline, and at the 6-year follow-up, women were in different stages of menopausal transition. Polysomnography was used to study sleep architecture at baseline and follow-up. The effects of aging and menopause (assessed as change in serum follicle-stimulating hormone [S-FSH]) on sleep architecture were evaluated using linear regression models. Results: After controlling for body mass index, vasomotor, and depressive symptoms, aging of 6 years resulted in shorter total sleep time (B −37.4, 95% confidence interval [CI] −71.5 to (−3.3)), lower sleep efficiency (B −6.5, 95%CI −12.7 to (−0.2)), as well as in increased transitions from slow-wave sleep (SWS) to wakefulness (B 1.0, 95%CI 0.1 to 1.9), wake after sleep onset (B 37.7, 95%CI 12.5 to 63.0), awakenings per hour (B 1.8, 95%CI 0.8 to 2.8), and arousal index (B 2.3, 95%CI 0.1 to 4.4). Higher S-FSH concentration in menopausal transition was associated with increased SWS (B 0.09, 95%CI 0.01 to 0.16) after controlling for confounding factors. Conclusions: A significant deterioration in sleep continuity occurs when women age from 46 to 52 years, but change from premenopausal to menopausal state restores some SWS.

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“…Indeed, insomnia can occur during menopause independent of nocturnal flashes. Although self-reported nocturnal flashes correlate with subjective poor sleep quality, such association is less clear when objective sleep measures are used [96,105,106]. There is only limited and contradictory evidence supporting an association between nocturnal flashes and sleep disturbance when both variables were measured objectively [96,[105][106][107][108][109][110][111].…”

Section: Menopausementioning

confidence: 99%

Nonpharmacological Treatment of Insomnia

Hohagen

1996

Sleep

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Insomnia is one of the most common sleep disorders, which is characterized by nocturnal symptoms of difficulties initiating and/or maintaining sleep, and by daytime symptoms that impair occupational, social, or other areas of functioning. Insomnia disorder can exist alone or in conjunction with comorbid medical and/or psychiatric conditions. The incidence of insomnia is higher in women and can increase during certain junctures of a woman's life (e.g., pregnancy, postpartum, and menopause). This article will focus on an overview of cognitive behavioral therapy for insomnia, evidence of effectiveness for this treatment when insomnia disorder is experienced alone or in parallel with a comorbidity, and a review with promising data on the use of cognitive behavioral therapy for insomnia when present during postpartum and menopause.

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Sleep Patterns and Stability in Perimenopausal Women

Cited by 171 publications

References 0 publications

Sex differences in sleep: impact of biological sex and sex steroids

Sex differences in sleep: impact of biological sex and sex steroids

Sleep During Menopausal Transition: A 6-Year Follow-Up

Nonpharmacological Treatment of Insomnia

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