Sleep in Parkinson's disease: A systematic review and meta-analysis of polysomnographic findings

Zhang, Ye; Ren, Rong; Sanford, Larry D.; Yang, Linghui; Zhou, Junying; Tan, Lu; Li, Taomei; Zhang, Jihui; Wing, Yun‐Kwok; Shi, Jie; Lü, Lin; Tang, Xiangdong

doi:10.1016/j.smrv.2020.101281

Cited by 89 publications

(80 citation statements)

References 140 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The proportion of patients with RBD was significantly higher in the group of PD patients with sleep apnea than in the group with PD without sleep apnea (94.7% vs. 63%). A meta-analysis of PSG findings in PD patients showed that they had decreased total sleep time, sleep efficiency, SWS and REM sleep and increased AHI, wake after sleep onset and PLM index [164]. A supplementary meta-analysis showed that PD with RBD was characterized by a decreased apnea index and increased PLM index and REM sleep.…”

Section: Rls With Pdmentioning

confidence: 99%

Current Update on Clinically Relevant Sleep Issues in Parkinson’s Disease: A Narrative Review

Suzuki

2021

JPD

View full text Add to dashboard Cite

Sleep disturbances are among the common nonmotor symptoms in patients with Parkinson’s disease (PD). Sleep can be disrupted by nocturnal motor and nonmotor symptoms and other comorbid sleep disorders. Rapid eye movement sleep behavior disorder (RBD) causes sleep-related injury, has important clinical implications as a harbinger of PD and predicts a progressive clinical phenotype. Restless legs syndrome (RLS) and its related symptoms can impair sleep initiation. Excessive daytime sleepiness (EDS) is a refractory problem affecting patients’ daytime activities. In particular, during the COVID-19 era, special attention should be paid to monitoring sleep problems, as infection-prevention procedures for COVID-19 can affect patients’ motor symptoms, psychiatric symptoms and sleep. Therefore, screening for and managing sleep problems is important in clinical practice, and the maintenance of good sleep conditions may improve the quality of life of PD patients. This narrative review focused on the literature published in the past 10 years, providing a current update of various sleep disturbances in PD patients and their management, including RBD, RLS, EDS, sleep apnea and circadian abnormalities.

show abstract

Section: Rls With Pdmentioning

confidence: 99%

Current Update on Clinically Relevant Sleep Issues in Parkinson’s Disease: A Narrative Review

Suzuki

2021

JPD

View full text Add to dashboard Cite

show abstract

“…Bailey et al October 2020 6 polysomnographic findings and therapeutic management of sleep disturbance in PD, and therefore we have only provided a brief overview below. 4,5 RBD is well characterised in PD populations with longitudinal case-control studies identifying 73.5% of patients with idiopathic RBD (iRBD) develop a neurodegenerative disorder after 12-years. 6 Those patients diagnosed with PD and RBD tend towards more severe clinical features, including increased motor symptom severity, higher rates of axial symptoms, psychiatric symptoms, hallucinations, autonomic dysfunction, cognitive impairment and impulse control disorders, as well as a generally longer motor disease duration, when compared to PD patients without RBD.…”

Section: Sleep Disturbance In Movement Disordersmentioning

confidence: 99%

Sleep disturbance in movement disorders: insights, treatments and challenges

Bailey

Hubbard

Fasano

et al. 2021

J Neurol Neurosurg Psychiatry

View full text Add to dashboard Cite

Sleep and circadian rhythm disturbances are central features of many movement disorders, exacerbating motor and non-motor symptoms and impairing quality of life. Understanding these disturbances to sleep is clinically important and may further our understanding of the underlying movement disorder. This review evaluates the current anatomical and neurochemical understanding of normal sleep and the recognised primary sleep disorders. In addition, we undertook a systematic review of the evidence for disruption to sleep across multiple movement disorders. Rapid eye movement sleep behaviour disorder has emerged as the most reliable prodromal biomarker for the alpha synucleinopathies, including Parkinson’s disease and multiple system atrophy, often preceding motor symptom onset by several years. Abnormal sleep has also been described for many other movement disorders, but further evidence is needed to determine whether this is a primary or secondary phenotypic component of the underlying condition. Medication used in the treatment of motor symptoms also affects sleep and can aggravate or cause certain sleep disorders. Within the context of movement disorders, there is also some suggestion of a shared underlying mechanism for motor and sleep pathophysiology, with evidence implicating thalamic and brainstem structures and monoaminergic neurotransmission. This review highlights the need for an understanding of normal and abnormal sleep within the movement disorder clinic, an ability to screen for specific causes of poor sleep and to treat sleep disturbance to improve quality of life. Key sleep disorders also act as important biomarkers and have implications in diagnosis, prognosis and the development of future therapies.

show abstract

“…For this reason, we focus on cheaper approaches. Some of the symptoms like sleep disorders are challenging to monitor due to carrying out tests with the usage of uncomfortable for patients' gold standard method -polysomnography [15].…”

Section: Related Workmentioning

confidence: 99%

Parkinson’s Disease Detection based on Changes of Emotions during Speech

Skibińska

Bürget

2020

2020 12th International Congress on Ultra Modern Telecommunications and Control Systems and Workshops (ICUMT)

View full text Add to dashboard Cite

Parkinson's disease (PD) is the neurodegenerative disease which affects 2-3 % of the population beyond 65 years of age in EU. When PD treatment is administered early, it is significantly more effective. Unfortunately, it is quite challenging to detect this disease at its early stage and when the symptoms can be recognized it is usually quite late. For this reason there is big motivation for development more accessible and accurate solutions for the detection of PD. One of the early symptoms is so-called hypomimia. This paper introduces an automatic method, which can objectively detect PD. The method is based on analysis of emotion changes during pronunciation defined speech exercises. We achieved balanced accuracy 69 % using XGBoost algorithm. As the exercise we proposed to use a Czech tongue twister-the difficult to pronounce sentence. The features can be explained and thus it can be used in clinical practice. We identified that the most valuable emotion for PD detection in this case is fear. 124 2020 12th International Congress on Ultra Modern Telecommunications and Control Systems and Workshops (ICUMT)

show abstract

Sleep in Parkinson's disease: A systematic review and meta-analysis of polysomnographic findings

Cited by 89 publications

References 140 publications

Current Update on Clinically Relevant Sleep Issues in Parkinson’s Disease: A Narrative Review

Current Update on Clinically Relevant Sleep Issues in Parkinson’s Disease: A Narrative Review

Sleep disturbance in movement disorders: insights, treatments and challenges

Parkinson’s Disease Detection based on Changes of Emotions during Speech

Contact Info

Product

Resources

About