Sleep fragmentation hypersensitizes healthy young women to deep and superficial experimental pain

The prevalence and potential determinants of dysmenorrhoea and other pelvic pain in women: a prospective study

“…Mental health disorders other than anxiety and depression may be associated with OPP (and other pain types) but these were not explored in this current study. However, an association, although nonsignificant, with poor sleep supports its potential contribution to the neurobiology of pain . We found modestly elevated nonsignificant ARRs for OPP with past chlamydia infection, endometriosis and dyspareunia.…”

“…Pelvic pain conditions are associated with increased pain sensitivity due to central changes in the nervous system, as well as other factors that affect the neurobiology of pain (e.g. sleep fragmentation) . This suggests that all may have common causal factors, especially when pain‐sensitising conditions are present (e.g.…”

Perioperative Pharmacological Sleep‐Promotion and Pain Control: A Systematic Review

“…Whereas experimental sleep deprivation and sleep disruption paradigms lead to increased pain sensitivity, the mechanisms that account for these neurophysiological alterations are incompletely understood. Emerging evidence shows that sleep fragmentation and total sleep deprivation may impair descending pain‐inhibitory capacity . We have recently found that 2 consecutive nights of forced awakenings enhances measures of central sensitization in a sex‐dependent manner such that males experience enhanced secondary hyperalgesia while females demonstrate enhanced temporal summation .…”

Pain in elite athletes—neurophysiological, biomechanical and psychosocial considerations: a narrative review

“…Pain can disrupt sleep, and sleep problems can worsen pain. A sleep-deprived athlete is not in an optimal state of recovery, and sleep deprivation can alter tissue sensitivity61 and load capacity, thereby increasing risk of injury and pain. In fact, athletes who sleep less than 8 hours per night increase their risk of injury by almost twofold 62…”