Sleep duration and atrial fibrillation risk in the context of predictive, preventive, and personalized medicine: the Suita Study and meta-analysis of prospective cohort studies

Arafa, Ahmed; Kokubo, Yoshihiro; Shimamoto, Keiko; Kashima, Rena; Watanabe, Emi; Sakai, Yukie; Li, Jiaqi; Teramoto, Masayuki; Sheerah, Haytham A.; Kusano, Kengo

doi:10.1007/s13167-022-00275-4

Cited by 13 publications

(10 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a prospective, urban-dwelling Japanese cohort (N=6898), short sleep (≤6 hours) and irregular sleep (eg, night-shift work) were associated with increased risks of AF (HR, 1.34 [95% CI, 1.01–1.77] and HR, 1.63 [95% CI, 1.16–2.30], respectively) compared with moderate sleep (7 hours) in multivariable-adjusted analyses over a median of 14.5 years of follow-up. 89…”

Section: Disorders Of Heart Rhythmmentioning

confidence: 99%

2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Martin,

Aday,

Almarzooq

et al. 2024

Circulation

240

View full text Add to dashboard Cite

BACKGROUND: The American Heart Association (AHA), in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, nutrition, sleep, and obesity) and health factors (cholesterol, blood pressure, glucose control, and metabolic syndrome) that contribute to cardiovascular health. The AHA Heart Disease and Stroke Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, brain health, complications of pregnancy, kidney disease, congenital heart disease, rhythm disorders, sudden cardiac arrest, subclinical atherosclerosis, coronary heart disease, cardiomyopathy, heart failure, valvular disease, venous thromboembolism, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs). METHODS: The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing. The 2024 AHA Statistical Update is the product of a full year’s worth of effort in 2023 by dedicated volunteer clinicians and scientists, committed government professionals, and AHA staff members. The AHA strives to further understand and help heal health problems inflicted by structural racism, a public health crisis that can significantly damage physical and mental health and perpetuate disparities in access to health care, education, income, housing, and several other factors vital to healthy lives. This year’s edition includes additional global data, as well as data on the monitoring and benefits of cardiovascular health in the population, with an enhanced focus on health equity across several key domains. RESULTS: Each of the chapters in the Statistical Update focuses on a different topic related to heart disease and stroke statistics. CONCLUSIONS: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.

show abstract

Section: Disorders Of Heart Rhythmmentioning

confidence: 99%

2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Martin,

Aday,

Almarzooq

et al. 2024

Circulation

240

View full text Add to dashboard Cite

show abstract

“…To our knowledge, this is the first study to prospectively explore the relationship between sleep behaviour traits and the risk of new-onset AF in patients with diabetes. Previous observational studies and meta-analyses have indicated that both short and long sleep durations are associated with an increased risk of AF [ 24 , 25 ]. Arafa et al reported that individuals who slept ≤ 6 h or ≥ 8 h per day had an increased risk of AF compared with those who slept 7 h per day [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

“…Previous observational studies and meta-analyses have indicated that both short and long sleep durations are associated with an increased risk of AF [ 24 , 25 ]. Arafa et al reported that individuals who slept ≤ 6 h or ≥ 8 h per day had an increased risk of AF compared with those who slept 7 h per day [ 24 ]. Morovatdar et al also suggest that unhealthy sleep duration (defined as < 6 h or > 8 h) could be associated with an increased risk of AF [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

Increased susceptibility to new-onset atrial fibrillation in diabetic women with poor sleep behaviour traits: findings from the prospective cohort study in the UK Biobank

Chen,

Liu,

Yan

et al. 2024

Diabetol Metab Syndr

View full text Add to dashboard Cite

Background Diabetic individuals often encounter various sleep-related challenges. Although the association between sleep duration and atrial fibrillation (AF) have been explored, the association of other sleep traits with the incidence of AF remains unclear. A comprehensive understanding of these traits is essential for a more accurate assessment of sleep conditions in patients with diabetes and the development of novel AF prevention strategies. Methods This study involved 23,785 patients with diabetes without any pre-existing cardiovascular disease, drawn from the UK Biobank. Sleep behaviour traits examined encompassed sleep duration, chronotype, insomnia, snoring and daytime sleepiness. Sleep duration was categorised into three groups: low (≤ 5 h), proper (6–8 h) and long (≥ 9 h). We assessed associations using multivariate Cox proportional risk regression models. Furthermore, four poor sleep behaviours were constructed to evaluate their impact on the risk of new-onset AF. Results Over a mean follow-up period of 166 months, 2221 (9.3%) new cases of AF were identified. Short (hazard ratio (HR), 1.28; 95% confidence interval (CI) 1.10–1.50) and long sleep durations (HR 1.16; 95% CI 1.03–1.32) consistently exhibited an elevated risk of AF compared to optimal sleep duration. Early chronotype, infrequent insomnia and daytime sleepiness were associated with 11% (HR 0.89; 95% CI 0.82–0.97), 15% (HR 0.85; 95% CI 0.77–0.95) and 12% (HR 0.88; 95% CI 0.81–0.96) reduced risk of new-onset AF, respectively. However, no significant association was found between snoring and the incidence of AF (HR 0.99; 95% CI 0.91–1.07). Conclusions In diabetic populations, sleep duration, chronotype, insomnia and daytime sleepiness are strongly associated with AF incidence. An optimal sleep duration of 6–8 h presents the lowest AF risk compared to short or long sleep duration. Additionally, poor sleep patterns present a greater risk of new-onset AF in women than in men.

show abstract

“…[14][15][16][17]25,27,28 Most prominently, sleep durationeither shorter or longer than the recommended 7-8 hoursis associated with incident AF. [28][29][30] Risk for incident AF may also vary based on the combination of adverse sleep symptoms. One metaanalysis of 14 million patients showed that self-report of both insomnia and frequent nighttime awakening was associated with a 30% higher risk of AF.…”

Section: Discussionmentioning

confidence: 99%

Insomnia and early incident atrial fibrillation: A 16-year cohort study of younger men and women Veterans

Gaffey

Rosman

Lampert

et al. 2023

Preprint

View full text Add to dashboard Cite

Background: There is growing consideration of sleep disturbances and disorders in early cardiovascular risk, including atrial fibrillation (AF). Obstructive sleep apnea (OSA) confers risk for AF but is highly comorbid with insomnia, another common sleep disorder. The objectives of this investigation were first, to determine the association of insomnia and early incident AF risk and second, to determine if AF onset is earlier among those with insomnia. Methods: This retrospective analysis used electronic health records from a cohort study of U.S. Veterans who were discharged from military service as of October 1, 2001 (i.e., post-9/11) and received Veterans Health Administration (VA) healthcare, 2001-2017. Time-varying, multivariate Cox proportional hazard models were used to examine the independent contribution of insomnia diagnosis to AF incidence while serially adjusting for demographics, lifestyle factors, clinical comorbidities including OSA, psychiatric disorders, and healthcare utilization. Results: Overall, 1,063,723 post-9/11 Veterans (Mage=28.2 years, 12% women) were followed for 10 years on average. There were 4168 cases of AF (0.42/1000 person-years). Insomnia was associated with a 32% greater, adjusted risk of AF (95% CI, 1.21-1.43), and Veterans with insomnia showed AF onset up to two years earlier. Insomnia-AF associations were similar after accounting for healthcare utilization, excluding Veterans with OSA, and among those with a sleep study (adjusted hazard ratios [aHR]: 1.29-1.34). Conclusion: In younger adults, insomnia was independently associated with incident AF even when accounting for OSA. Additional studies should determine if this association differs by sex and if behavioral or pharmacological treatment for insomnia attenuates AF risk.

show abstract

Sleep duration and atrial fibrillation risk in the context of predictive, preventive, and personalized medicine: the Suita Study and meta-analysis of prospective cohort studies

Cited by 13 publications

References 49 publications

2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Increased susceptibility to new-onset atrial fibrillation in diabetic women with poor sleep behaviour traits: findings from the prospective cohort study in the UK Biobank

Insomnia and early incident atrial fibrillation: A 16-year cohort study of younger men and women Veterans

Contact Info

Product

Resources

About