Sleep disturbances in depressed and nondepressed pregnant women

Abstract

Background Sleep disturbances and symptoms of depression are common during pregnancy. Both are independent and interrelated risk factors for adverse outcomes. It is unclear the degree to which sleep differs between depressed and non-depressed pregnant women. We sought to 1), describe and compare sleep disturbances in depressed pregnant and non-depressed pregnant women, 2) determine the impact of selective serotonin reuptake inhibitors (SSRI) treatment on sleep, and 3)evaluate whether sleep at 20 weeks is associated with increased depressive symptoms and major depressive disorder (MDD) in later pregnancy. Methods Pregnant women (N = 240) were recruited in the second trimester (20 weeks gestation) and assigned to depressed (N = 59) and non-depressed (N = 181) groups based on a SCID diagnosis of major depressive disorder. The Structured Interview Guide for the Hamilton Rating Scale with Atypical Depression Supplement (SIGH-ADS) was administered at 20, 30 and 36 weeks gestation from which the sleep variables were obtained. Results Depressed women had more fragmented sleep at each assessment (p values ≤ .05). However, the frequency of insomnia symptoms was greater for depressed women only at 20 weeks gestation. SSRI use, regardless of MDD status, did significantly affect several sleep variables. Among the non-depressed women, those with short or longer sleep duration, symptoms of insomnia and long periods of nocturnal waketime had higher SIGH-ADS scores later in pregnancy (p values = < .05). Conclusions At 20 and 30 weeks gestation sleep was more disturbed in depressed pregnant women compared to non-depressed pregnant women. At 36 weeks, sleep was disturbed regardless of depression status or SSRI use. Among the non-depressed women, disturbed sleep in conjunction with SSRI use was associated with higher depressive symptoms.

Determinants of sleep quality among pregnant women in China: A cross-sectional survey

“…Prenatal depression as well as postpartum depression were strongly linked with sleep quality [12]. Consistent with this, depressive pregnant women reportedly have various types of insomnia symptoms and decreased sleep efficiency [13,14]. department of obstetrics and gynecology of two teaching hospitals in central China between December 2013 and July 2014.…”

Identifying Insomnia in Early Pregnancy: Validation of the Insomnia Symptoms Questionnaire (ISQ) in Pregnant Women

“…Evidence supports the conviction that an increasing number of women report insomnia symptoms following conc eption. [18][19][20] Although the majority of the evidence indicates that the third trimester confers the greatest risk for developing i nsomnia, 19,21 few studies have assessed sleep in early pregnancy and none have evaluated the prevalence of a case defi nition of insomnia. We contend that a substantial number of women are at risk of developing insomnia in early pregnancy based on the myriad physiological and psychological changes that occur.…”

Qualidade do sono em gestantes com sobrepeso

“…MÉTODOS: Estudo transversal incluindo 223 gestantes com ≥14 semanas: 105 com sobrepeso (índice de massa corporal -IMCpré-gestacional ≥25,0 km 2 ) e 118 eutróficas (IMC 18,(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)9 kg/m 2 ) em acompanhamento pré-natal. A versão brasileira do questionário Pittsburgh Sleep Quality Index (PSQI-BR) foi utilizada para avaliação do sono.…”

“…As alterações do sono durante a gestação têm sido associadas a diversos problemas de saúde para o binômio materno-fetal. A insônia durante a gestação está associada a depressão e ansiedade no final da gestação e do puerpério 14,15 , baixa produtividade diurna e riscos para a segurança 15 , parto pré-termo 16,17 , trabalho de parto prolongado e cesárea 18,19 . A insônia pode ainda alterar o relacionamento da gestante com o parceiro e a família 20 .…”