Sleep disturbances and sleep disorders in adults living with chronic pain: a meta-analysis

Mathias, J.; Cant, Megan L.; Burke, Ann E.

doi:10.1016/j.sleep.2018.05.023

Cited by 198 publications

(170 citation statements)

References 84 publications

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“…Some studies indicate that the prevalence increases with age and is rising overall . Chronic pain is known to have a major impact on patients’ well‐being, relationships with others, ability to carry out everyday activities, and work productivity . The associated economic burden to society exceeds $500 billion annually in the United States and consumes 2%‐10% of GDP in European countries …”

Section: Introductionmentioning

confidence: 99%

“…1,[4][5][6][7][8][9][10] Chronic pain is known to have a major impact on patients' well-being, relationships with others, ability to carry out everyday activities, and work productivity. 3,[11][12][13][14][15][16][17][18][19] The associated economic burden to society exceeds $500 billion annually in the United States and consumes 2%-10% of GDP in European countries. [20][21][22][23] The treatment of chronic pain is complex and challenging, encompassing many disciplines, including physical and psychological therapies, as well as pharmacological, interventional, and surgical treatments.…”

Section: Introductionmentioning

confidence: 99%

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Pain relief and improvement in quality of life with 10 kHz SCS therapy: Summary of clinical evidence

et al. 2020

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Objective Chronic pain is a prevalent condition which has a significant effect on the lives of those it impacts. High‐frequency 10 kHz spinal cord stimulation (10 kHz SCS) has been shown to provide paresthesia‐free pain relief for a wide variety of pain indications. This article summarizes the current and emerging data as they relate to the clinical use of the therapy in various pain syndromes. Methods A literature search was conducted using the PubMed electronic database using keywords related to 10 kHz SCS. The database was queried from 2013 to May 2019. Articles reporting clinical studies that included human subjects permanently treated with 10 kHz SCS (Senza® system) were included in the review. Recent and relevant conference proceedings known to the authors were also included. Results The selected literature demonstrated significant evidence for the efficacy of 10 kHz SCS in treating chronic back and leg pain (CBLP), including a randomized, controlled trial as well as prospective and retrospective studies. One‐year follow‐up responder rates (pain relief ≥50%) ranged from 60% to 80%. Other studies and case series showed promising outcomes in specific conditions, including nonsurgical refractory back pain, neuropathic limb pain, complex regional pain syndrome, chronic widespread pain, chronic pelvic pain, and intractable headache. Subgroup analyses also pointed toward the potential of 10 kHz SCS being successful when low‐frequency SCS has failed. The vast majority of these studies reported improved quality of life (QOL) metrics and/or reduced opioid consumption. Conclusions Level I evidence already exists for the efficacy of 10 kHz SCS in treating CBLP, supported by real‐world clinical experience. Other studies demonstrate the potential of the therapy across a range of chronic pain etiologies, although larger confirmatory studies are recommended. Overall, the literature suggests that the therapy is associated with improved QOL as well as reduced opioid consumption.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Pain relief and improvement in quality of life with 10 kHz SCS therapy: Summary of clinical evidence

et al. 2020

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“…According to a current meta-analysis, the pooled prevalence of sleep disorders among arthritis patients was 44%, making it the most prevalent comorbidity. 12 Considering that the arthritis prevalence was above 35% in South Korea, sleep disturbance due to pain or inflammation derived from arthritis is problematic. 13,14 Meanwhile, vitamin D plays a central role in bone and cartilage metabolism and pain management, through beneficial effects on inflammation and neurotransmitters; 15,16 vitamin D deficiency is associated with arthritis, which negatively affects sleep.…”

Section: Introductionmentioning

confidence: 99%

<p>Associations of 25-Hydroxyvitamin D Levels and Arthritis with Sleep Duration: The Korean National Health and Nutrition Examination Survey 2008–2014</p>

Kim

Lee

Lim

et al. 2020

NSS

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Purpose: The mean sleep duration of Koreans is 7 hours 49 minutes, which is the lowest among Organization for Economic Cooperation and Development countries. Although vitamin D deficiency and arthritis are considered modifiable factors influencing restorative sleep, mean vitamin D levels are low (17.33 ng/mL) and arthritis is prevalent among Koreans. This study investigated whether vitamin D deficiency and arthritis increase the risk of short sleep duration. Patients and Methods: The current study used data from the Korean National Health and Nutrition Examination Survey (KNHANES) for 46,405 Korean adults. Vitamin D levels were measured using a radioimmunoassay kit. Sleep duration and arthritis history were assessed using a self-reported questionnaire. Sleep duration was categorized as optimal (7 to <9 hours/day), short (<7 hours/day), and long (≥9 hours/day). Vitamin D levels were grouped as vitamin D sufficiency (≥20 ng/mL), insufficiency (10-19.99 ng/mL), and deficiency (<10 ng/mL). Multiple imputation was used to compensate for missing data. Multinomial logistic regression was used to examine the associations of vitamin D and arthritis status with sleep duration. The regressions were adjusted for covariates, and each model was adjusted for vitamin D and arthritis. Results: Among these participants, 23,078 (49.73%) and 3518 (7.58%) had short and long sleep duration, respectively; 26,724 (57.59%) and 4349 (9.37%) exhibited vitamin D insufficiency and deficiency, respectively; and 4709 (10.15%) were arthritis patients. Compared with vitamin D sufficiency, vitamin D insufficiency and deficiency were associated with short sleep duration (vitamin D insufficiency group: OR = 1.07, 95% CI = 1.01-1.13; vitamin D deficiency group: OR = 1.13, 95% CI = 1.03-1.24). The presence of arthritis was associated with short sleep duration (OR = 1.14, 95% CI = 1.06-1.22) compared with its absence. The interaction between vitamin D deficiency and the presence of arthritis was significantly associated with short sleep duration. However, long sleep duration was not significantly associated with vitamin D levels or arthritis status. Conclusion: Low vitamin D levels and the presence of arthritis were associated with an increased risk of short sleep duration. Additionally, there was a positive interaction effect between vitamin D deficiency and arthritis on short sleep duration.

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“…In mechanical, interventional and epidemiological studies alike, considerable effort has been devoted to progressively shed light on the relationship between sleep and pain [8,[11][12][13][14][15][16][17]. For example, a recent meta-analysis with pooled estimates from 37 studies using polysomonography in populations with persistent pain, reported a 72% prevalence of insomnia [18]. This interrelation between sleep and pain is echoed in recent reviews [8,13,19], which, in contrast to previous studies investigating (bi)directionality, highlights a more consistent unidirectional effect of poor sleep on pain exacerbation and vulnerability.…”

Section: Introductionmentioning

confidence: 99%

Poor Sleep Is a Risk Factor for Low-Back Pain among Healthcare Workers: Prospective Cohort Study

Vinstrup

Jakobsen

Andersen

2020

IJERPH

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This study aimed to investigate the association between poor sleep and risk of low-back pain (LBP) in healthcare workers. Using a prospective cohort design with 1-year follow-up, a total of 1955 healthcare workers (60% nurses) from 389 departments at 19 hospitals responded to questionnaires containing items related to lifestyle, health, and working environment. Associations between sleep scores (0–100) at baseline and LBP intensity (0–10) at follow-up were modelled using cumulative logistic regression accounting for clustering at the department level and adjusted for lifestyle and psychosocial confounders. In the full population of healthcare workers, 43.9% and 24.4% experienced moderate and poor sleep, respectively. In the fully adjusted model with good sleep as reference, moderate, and poor sleep increased the risk of LBP at follow-up, with odds ratios (OR’s) of 1.66 (95% confidence interval (CI) 1.35–2.04) and 2.05 (95% CI 1.57–2.69), respectively. Three sensitivity analyses including healthcare workers free from LBP, nurses, and nurses free from LBP at baseline, respectively, yielded similar results. In conclusion, poor sleep constitutes a potent risk factor for LBP among healthcare workers. The presented results provide strong incentives to evaluate and weigh current prevention policies against an updated biopsychosocial framework.

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Sleep disturbances and sleep disorders in adults living with chronic pain: a meta-analysis

Cited by 198 publications

References 84 publications

Pain relief and improvement in quality of life with 10 kHz SCS therapy: Summary of clinical evidence

Pain relief and improvement in quality of life with 10 kHz SCS therapy: Summary of clinical evidence

<p>Associations of 25-Hydroxyvitamin D Levels and Arthritis with Sleep Duration: The Korean National Health and Nutrition Examination Survey 2008–2014</p>

Poor Sleep Is a Risk Factor for Low-Back Pain among Healthcare Workers: Prospective Cohort Study

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