Sleep disturbance in generalized anxiety disorder and its treatment

Monti, Jaime M.; Monti, Daniel

doi:10.1053/smrv.1999.0096

Cited by 188 publications

(107 citation statements)

References 43 publications

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“…[15][16][17] In the primary anxiety and bipolar groups, this was accompanied by a delayed activity peak in the afternoon. The primary anxiety group also presented a lower b suggestive of a slower fall and rise of activity levels in the evening and morning.…”

Section: Discussionmentioning

confidence: 99%

“…Studies focusing on individuals with anxiety have highlighted sleep initiation and maintenance (i.e., fragmented or poorly consolidated sleep) difficulties. [15][16][17] Similarly, in both community-based and clin ical samples, depression has been associated with prolonged sleep onset latency, poorer sleep consolidation, extended or delayed sleep duration and phase shifts of the sleep-wake cycle. 14,[18][19][20][21][22][23][24] Compared with age-matched controls, young people with bipolar disorder have longer sleep onset latency and increased nighttime awakenings, and they report worse sleep quality and spending extended time asleep.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Ambulatory sleep-wake patterns and variability in young people with emerging mental disorders

Robillard

Hermens

Naismith

et al. 2015

jpn

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Ambulatory sleep-wake patterns and variability in young people with emerging mental disorders

Robillard

Hermens

Naismith

et al. 2015

jpn

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“…46 Medications used to treat depression, such as selective serotonin reuptake inhibitors, tricyclic antidepressants and monoamine oxidase inhibitors 41,45 are also known to suppress REM sleep, yet no patients in our mild TBI analysis were medicated.…”

Section: Discussionmentioning

confidence: 99%

Sleep Disturbances in Traumatic Brain Injury: A Meta-Analysis

Grima

Ponsford

Rajaratnam

et al. 2016

Journal of Clinical Sleep Medicine

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Study Objectives: Sleep disturbances are frequently reported following traumatic brain injury (TBI); however, the exact disturbances remain unclear. This meta-analysis aimed to characterize sleep disturbance in community dwelling patients with TBI as compared to controls. Methods: Two investigators independently conducted a systematic search of multiple electronic databases from inception to May 27, 2015. Studies were selected if they compared sleep in community dwelling individuals with TBI relative to a control population without head injury. Data were pooled in metaanalysis with outcomes expressed as the standard mean difference (SMD) and 95% confidence interval (CI). The primary outcomes were derived from polysomnography and secondary outcomes were derived from subjective sleep measures. Results: Sixteen studies were included, combining 637 TBI patients and 567 controls, all of whom were community dwelling. Pooled polysomnography data revealed that TBI patients had poorer sleep efficiency (SMD = −0. I NTRO DUCTI O NSleep disturbances are frequently reported following traumatic brain injury (TBI), with over 50% of people experiencing some form of sleep disturbance post TBI.1 Although a large majority of people with TBI generally make a good physical recovery, disrupted sleep can often go untreated, impacting quality of life, impeding rehabilitation and return to pre-injury activities.2-5 Our recent work showed significant interrelationships between daytime sleepiness, daytime fatigue, cognitive impairment, and mood disturbances in TBI. 6 While individuals with TBI are known to report sleep problems, 1 the specific changes to sleep remain poorly characterized.7 Studies have been limited by small sample sizes, with variable and inconsistent findings. [8][9][10][11][12] This makes for a difficult characterization of sleep post TBI. Thus, there is a need to establish the specific aspects of sleep that are most affected post TBI as these have important implications for treatment and rehabilitation. The aim of the current meta-analysis was to characterize both objective sleep disturbances and subjective sleep complaints in individuals with TBI relative to healthy controls. Study outcomes included the comparison of TBI patients to controls across both polysomnography and subjective measures of sleep. It ; Matthew P. Pase, PhD was hypothesized that those with TBI would display widespread objective and subjective sleep deficits as compared to controls without head injury. The present study aimed to summarize current literature, which would identify important avenues for future research. M ETHO DS Study DesignThe search strategy was conducted in accordance with the meta-analysis of observational studies in epidemiology guidelines. 13 Article SearchingOvid Medline, Embase, PsychInfo, Scopus, and the Cochrane Library were systematically searched until May, 27 2015. The search was initially developed by all authors and refined by a librarian at Monash University. The references of recent publications were also hand searc...

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“…were almost within the normal physiological limits 19 . Some studies however revealed inconclusive reports; either increase or decrease in NREM S1, NREM S2, NREM S4, changes in NREM S3 and REM sleep, etc 4 . Differences observed in both subjective and objective sleep assessments could be associated with sleep disturbances in the patients.…”

Section: Discussionmentioning

confidence: 99%

“…Relatively little research has been focused on sleep disturbances in anxiety disorders compared to affective disorders. Disturbances in sleep such as trouble in falling asleep or staying asleep, increased daytime fatigue, decreased sleep efficiency, increased sleep latencies, intermittent awakenings, reduced slow wave sleep (SWS) and rapid eye movement (REM) sleep states have been reported in patients with GAD 1,3,4 . Though sleep disturbances are reported in patients with social phobias, polysomnographic studies to ascertain the sleep architecture among GAD patients with co-morbid social phobia are scanty.…”

Section: Introductionmentioning

confidence: 99%

<i>Manasamitra vataka</i> and <i>Shirodhara</i> Treatments Preserve Slow Wave Sleep and Promote Sleep Continuity in Patients with Generalized Anxiety Disorder and Co-Morbid Generalized Social Phobia

et al. 2016

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This study demonstrates the clinical efficacy of Manasamitra Vataka and Shirodhara (Ayurvedic treatments) over clonazepam in preserving slow wave sleep and promoting sleep quality in patients of generalized anxiety disorder (GAD) with co-morbid generalized social phobia. Whole night polysomnography was carried out to assess the sleep architecture and spindledelta dynamics. The study highlights the sleep promoting and preserving nature of Manasamitra Vataka and Shirodhara in GAD patients with co-morbid generalized social phobia. Ayurvedic treatments were helpful in improving the subjective quality of sleep and preserve sleep organization. Further studies are needed to confirm the potential of Ayurvedic interventions as a treatment of choice in the management of anxiety disorders.

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Sleep disturbance in generalized anxiety disorder and its treatment

Cited by 188 publications

References 43 publications

Ambulatory sleep-wake patterns and variability in young people with emerging mental disorders

Ambulatory sleep-wake patterns and variability in young people with emerging mental disorders

Sleep Disturbances in Traumatic Brain Injury: A Meta-Analysis

<i>Manasamitra vataka</i> and <i>Shirodhara</i> Treatments Preserve Slow Wave Sleep and Promote Sleep Continuity in Patients with Generalized Anxiety Disorder and Co-Morbid Generalized Social Phobia

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