Sleep Disturbance as a Predictor of Accelerated Human Aging

Abstract

Introduction. One of the main predictors of aging is sleep disturbance, the study of the role of which in the development of the accelerated aging process is recognized as an urgent problem for the medical community.The aim of the work is to analyze modern data on age-related aspects of sleep status and describe known markers of early aging associated with somnological disorders.Materials and methods. The search and selection of literary sources was carried out in the databases PubMed, eLibrary, CyberLeninka, Google Scholar. Search depth — 17 years, from 2007 to 2024. The total number of publications included in the review was 80.Results and discussion. Aging refers to a general pathological process that affects all human physiological systems. Differences between the terms biological and chronobiological age are established. The role of somnological disorders in the accelerated aging process has been determined. It has been established that as age increases, changes in the electrophysiological pattern of sleep are observed. It was found that changes in biological markers of aging are positively correlated with sleep disturbance. The importance of neuroimaging methods in determining the accelerated rate of aging in people with sleep disorders is shown.Conclusion. Sleep disturbance is defined as a significant indicator of accelerated aging of the body. Further research into changes in the structure and quality of sleep may change the understanding of the pathogenetic mechanisms of aging and contribute to the development of new diagnostic and therapeutic strategies in the field of anti-aging medicine.