2021
DOI: 10.23866/brnrev:2019-0026
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Sleep Apnoea and Cancer: Is There a Relationship?

Abstract: In recent decades, obstructive sleep apnoea (OSA) has come to represent a major public health problem due to its prevalence and its health consequences. Although the association between OSA and cardiovascular morbidity and mortality is well recognized, its role as a promoter for the development and extension of neoplasms is less known. In recent years, intensive research on the subject has been developed. Bench and animal studies demonstrate how sleep fragmentation and intermittent hypoxia, characteristic phen… Show more

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“…The Late Antiquity and the Middle Ages (5 th -15 th centuries CE) signified the progressive southward expansion of Christian cultures and the unification of monarchies, followed by the consolidation of the modern geographical and political configuration. After the Middle Ages, the kingdoms of the IP shifted from colonized to colonizer countries and expanded their dominions all over the world, with emphasis on the American continent, a situation that remained until the 19 th -20 th centuries CE (Marín, 1995).…”
Section: The Iberian Peninsula: Biogeographical and Historical Contextmentioning
confidence: 99%
“…The Late Antiquity and the Middle Ages (5 th -15 th centuries CE) signified the progressive southward expansion of Christian cultures and the unification of monarchies, followed by the consolidation of the modern geographical and political configuration. After the Middle Ages, the kingdoms of the IP shifted from colonized to colonizer countries and expanded their dominions all over the world, with emphasis on the American continent, a situation that remained until the 19 th -20 th centuries CE (Marín, 1995).…”
Section: The Iberian Peninsula: Biogeographical and Historical Contextmentioning
confidence: 99%