Sleep and Circadian Health of Critical COVID-19 Survivors 3 Months After Hospital Discharge

Moncusí‐Moix, Anna; Vaca, Rafaela; Gort‐Paniello, Clara; Mínguez, Olga; Santisteve, Sally; Carmona, Paola; Torres, Gerard; Fagotti, Juliane; Labarca, Gonzalo; Torres, Antoni; González, Jessica; Gonzalo‐Calvo, David de; Barbé, Ferrán; Targa, Adriano

doi:10.1097/ccm.0000000000005476

Cited by 25 publications

(31 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…When should we consider screening patients for potential sleep interventions? Perhaps 90 days, as in the current study by Benítez et al ( 5 ), is the right time.…”

Section: What About Non-covid Critical Care?supporting

confidence: 51%

“…Compared with Benítez et al ( 5 ), Wilcox et al ( 4 ) found a greater disruption at 7 days with significant improvement by 6 months that was maintained at 12 months. When should we consider screening patients for potential sleep interventions?…”

Section: What About Non-covid Critical Care?mentioning

confidence: 81%

“…In this issue of Critical Care Medicine , Benítez et al ( 5 ) followed 172 consecutive patients admitted to their ICU in Spain with COVID-19 infection. No experimental interventions were made.…”

Section: Covid-19 Critical Illness Disrupts Sleep and Circadian Rhythmmentioning

confidence: 99%

“…It should be noted that the actigraphy was performed on a random subset of patients whose demographic and outcome characteristics were no different than the larger 172 patient population. The study by Benítez et al ( 5 ) is further limited, as are most critical care studies, by a lack of precritical illness baseline data. Finally, the study Benítez et al ( 5 ) is observational, and can therefore not confirm causal relationships, nor can it differentiate the effects of critical care interventions from the effects of SARS-CoV-2 infection ( 5 ).…”

Section: Covid-19 Critical Illness Disrupts Sleep and Circadian Rhythmmentioning

confidence: 99%

“…The study by Benítez et al ( 5 ) is further limited, as are most critical care studies, by a lack of precritical illness baseline data. Finally, the study Benítez et al ( 5 ) is observational, and can therefore not confirm causal relationships, nor can it differentiate the effects of critical care interventions from the effects of SARS-CoV-2 infection ( 5 ).…”

Section: Covid-19 Critical Illness Disrupts Sleep and Circadian Rhythmmentioning

confidence: 99%

See 4 more Smart Citations

COVID-19, Critical Illness, and Sleep*

Chatterjee

2022

Critical Care Medicine

View full text Add to dashboard Cite

While acute respiratory distress syndrome has been the most-reported severe complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, there is mounting evidence that this infection can affect the nervous system. This includes excessive daytime sleepiness, anxiety, depression, fatigue, muscle weakness, and elevated scores on the Pittsburgh Sleep Quality Index (PSQI). Sleep problems affect between 30% and 60% of COVID-19 patients (1).In an international survey of over 25,000 people that compared pre-pandemic sleep to intra-pandemic sleep, the prevalence of disrupted sleep increased from 14% to 28%. For those patients with self-reported COVID infection (800 patients), it was increased from 14% to 32%. Excessive sleepiness increased to 40% from 18% in post-infection patients (2).As most practicing intensivists already know, critically ill patients have significant sleep disruptions that contribute to ICU delirium. While many zeitgebers and interventions like vital sign checks, noise, procedures, and sedation have been implicated, invasive mechanical ventilation has a disproportionate contribution (3). These disruptions have been shown to persist up to a week after ICU discharge. While they do improve over time, they do not appear return to normal, even after 12 months (4). The natural question then arises, is there an additive effect of critical illness, mechanical ventilation, and SARS-COV-2 infection? COVID-19 CRITICAL ILLNESS DISRUPTS SLEEP AND CIRCADIAN RHYTHMIn this issue of Critical Care Medicine, Benítez et al ( 5) followed 172 consecutive patients admitted to their ICU in Spain with COVID-19 infection. No experimental interventions were made. The usual demographic and clinical data were obtained (e.g., age, ventilator days, ICU length of stay [LOS], etc.). Studyspecific data were collected during a research visit with surviving patients at day 90: PSQI (seven category subsets of 19 questions); Epworth Sleepiness Scale; Satisfaction Alertness Timing Efficiency Duration (sleep quality survey); actigraphy (7 d with total sleep time [TST], intradaily variability [IV] for sleep fragmentation, and interdaily stability [IS] for circadian rhythm); carbon monoxide diffusion coefficient; chest CT scan; Hospital Anxiety and Depression Scale (HADS); and 6-minute walk test for distance (6MWD). The statistical analysis was appropriate.

show abstract

“…When should we consider screening patients for potential sleep interventions? Perhaps 90 days, as in the current study by Benítez et al ( 5 ), is the right time.…”

Section: What About Non-covid Critical Care?supporting

confidence: 51%

Section: What About Non-covid Critical Care?mentioning

confidence: 81%

Section: Covid-19 Critical Illness Disrupts Sleep and Circadian Rhythmmentioning

confidence: 99%