Skull Metastasis from the Liver: Case Report and Literature Review

Han, Shuo; Zhang, Xiaohua; Lv, Tao; Han, Dong-Hua

doi:10.1016/j.wneu.2017.08.104

Cited by 3 publications

(1 citation statement)

References 15 publications

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“…However, two of the cases showed no signs of primary or metastatic lesions, which undoubtedly added difficulty to the diagnosis, which was finally defined by craniotomy. 25,26 In the reported cases, 59.3% (16/27) of the patients accepted craniotomy, 18.5% (5/27) biopsy, 29.6% (8/27) radiotherapy, 11.1% (3/27) chemotherapy, 7.4% (2/27) systemic therapy, sorafenib,…”

Section: Discussionmentioning

confidence: 99%

Response of Scalp and Skull Metastasis to Anti-PD-1 Antibody Combined with Regorafenib Treatment in a Sorafenib-Resistant Hepatocellular Carcinoma Patient and a Literature Review

Long¹,

Zhang²,

Wang³

et al. 2022

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Section: Discussionmentioning

confidence: 99%

Response of Scalp and Skull Metastasis to Anti-PD-1 Antibody Combined with Regorafenib Treatment in a Sorafenib-Resistant Hepatocellular Carcinoma Patient and a Literature Review

Long¹,

Zhang²,

Wang³

et al. 2022

OTT

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Solitary skull metastasis mimicking a meningioma with dural tail sign as the initial presentation of hepatocellular carcinoma: A case report and a brief review

Sun

Tsai

Huang

et al. 2021

Interdisciplinary Neurosurgery

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Superior Sagittal Sinus Tumor Eroding through the Skull: An Unfamiliar Presentation of Hepatocellular Carcinoma and Literature Review

Sadik

Dayoub

Bonatti³

2019

Case Reports in Surgery

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Background Hepatocellular carcinoma (HCC) most commonly develops in patients with liver cirrhosis caused by hepatitis C and B virus. HCC is the most common cause of death in people with cirrhosis. The lungs, bone, and lymph nodes are frequent sites of metastasis of HCC. Patients and Methods We present a case of solitary skull metastasis as the first symptom of HCC. A literature review with regard to HCC skull metastasis was undertaken. Results This patient had HCC based on chronic hepatitis C. He presented with an erosive lesion masquerading as a scalp lipoma resulting in hepatocellular carcinoma with retrograde reflux and sinus metastases. The lesion was ultimately resected, but the patient died within one week from liver failure. Seventeen similar cases were found in the literature. Median age of the patients was 58 years with 95% being male and 35% having viral hepatitis. Surgery was the preferred treatment with chemotherapy and radiation being other options. Outcome was acceptable but baseline liver disease is a limiting factor. Discussion Cranial metastases of HCC are rare but should be considered in patients with chronic hepatitis C presenting with scalp skin lesions.

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Skull Metastasis from the Liver: Case Report and Literature Review

Cited by 3 publications

References 15 publications

Response of Scalp and Skull Metastasis to Anti-PD-1 Antibody Combined with Regorafenib Treatment in a Sorafenib-Resistant Hepatocellular Carcinoma Patient and a Literature Review

Response of Scalp and Skull Metastasis to Anti-PD-1 Antibody Combined with Regorafenib Treatment in a Sorafenib-Resistant Hepatocellular Carcinoma Patient and a Literature Review

Solitary skull metastasis mimicking a meningioma with dural tail sign as the initial presentation of hepatocellular carcinoma: A case report and a brief review

Superior Sagittal Sinus Tumor Eroding through the Skull: An Unfamiliar Presentation of Hepatocellular Carcinoma and Literature Review

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