Skull-Base Tumors and Related Disorders

Bossche, Stephanie Vanden; Pretorius, Elias; Foer, Bert De

doi:10.1007/978-3-319-61423-6_60-1

Cited by 2 publications

(43 citation statements)

References 25 publications

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“…The skull base is perforated by numerous foramina, which allow the passage of vessels and nerves and provide communication between the intracranial and extracranial compartments. These are important sites to scrutinize on the imaging evaluation of the skull base, as the cranial nerves can also be a source of pathology and represent an important pathway for disease extension [ 2 , 3 ].…”

Section: Anatomic Considerationsmentioning

confidence: 99%

“…Meningiomas that abut the base of the skull are associated with focal hyperostosis, possibly secondary to osteoblastic stimulating factors, tumoral invasion, or a combination of both, although the definite pathogenesis is not fully understood [ 2 ]. The enlargement of adjacent paranasal sinuses has also been associated with anterior cranial fossa meningiomas, particularly along the planum sphenoidale, where there may be an upward blistering of the sphenoid sinus (pneumosinus dilatans).…”

Section: Skull Base Tumorsmentioning

confidence: 99%

“…Higher-grade meningiomas may demonstrate lytic and destructive features; however, alternative pathologies such as solitary fibrous tumor or metastasis should also be considered in such cases. MR spectroscopy does not play a routine role in diagnoses, but short TE proton ( 1 H) MR spectroscopy may show an alanine peak at 1.3–1.5 ppm and increased glutamine and glutamate peaks, which may be useful in equivocal cases [ 2 ].…”

Section: Skull Base Tumorsmentioning

confidence: 99%

“…ABCs are rare in the skull base. They can develop de novo or secondary to other skull base lesions, such as giant cell tumors, and are typically diagnosed in adolescents [ 2 ]. The 2020 WHO Classification of Tumors of Bone introduced revised terminology, proposing the use of ‘ABC’ and ‘ABC-like changes’ instead of the previously used terms ‘primary ABC’ and ‘secondary ABC’, respectively.…”

Section: Skull Base Tumorsmentioning

confidence: 99%

“…Imaging is therefore critical in the detection and differential diagnosis and can characterize lesions according to the site of origin, growth pattern, and tissue characteristics. In particular, magnetic resonance imaging (MRI), with conventional and advanced sequences, is a robust tool that can accurately define the lesion extent, which is essential for selecting optimal treatment strategies, anticipating surgical complications, and delineating targets for radiation therapy [ 1 , 2 , 3 ]. Both computed tomography (CT) and MRI have distinct advantages and disadvantages and are often complementary.…”

Section: Introductionmentioning

confidence: 99%

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Imaging of Skull Base Tumors

Battal

Zamora

2023

Tomography

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The skull base provides a platform for supporting the brain while serving as a conduit for major neurovascular structures. In addition to malignant lesions originating in the skull base, there are many benign entities and developmental variants that may simulate disease. Therefore, a basic understanding of the relevant embryology is essential. Lesions centered in the skull base can extend to the adjacent intracranial and extracranial compartments; conversely, the skull base can be secondarily involved by primary extracranial and intracranial disease. CT and MRI are the mainstay imaging methods and are complementary in the evaluation of skull base lesions. Advances in cross-sectional imaging have been crucial in the management of patients with skull base pathology, as this represents a complex anatomical area that is hidden from direct clinical exam. Furthermore, the clinician must rely on imaging studies for therapy planning and to monitor treatment response. It is crucial to have a thorough understanding of skull base anatomy and its various pathologies, as well as to recognize the appearance of treatment-related changes. In this review, we aim to describe skull base tumors and tumor-like lesions in an anatomical compartmental approach and present imaging methods that aid in diagnosis, management, and follow-up.

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Section: Anatomic Considerationsmentioning

confidence: 99%

Section: Skull Base Tumorsmentioning

confidence: 99%

Section: Skull Base Tumorsmentioning

confidence: 99%

Section: Skull Base Tumorsmentioning

confidence: 99%