SKRINING FITOKIMIA DARI EKSTRAK BUAH BUNCIS (Phaseolus vulgaris L) DALAM SEDIAAN SERBUK

Nugrahani, Rizki; Andayani, Yayuk; Hakim, Aliefman

doi:10.29303/jppipa.v2i1.38

Cited by 36 publications

(43 citation statements)

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“…Therefore, this test can show the presence of active compounds which are antifungal in the lengkuas rhizome extract, the presence of phenol compounds which is indicated by yellowish green discoloration (there is a change in color) when FeCl3 is added. The reactions that occur are expressed as follows: FeCl3 (aq) + 6 ArOH (s) → 6H + + 3Cl -+ [Fe (Oar) 6] 3-(aq) (Nugrahani et al, 2016). In this study, there was a change in color.…”

Section: Phenol Compound Screening Testmentioning

confidence: 73%

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STANDARDIZATION OF EXTRACT AND CHARACTERIZATION OF EMULGEL FORMULA OF LENGKUAS (Alpinia galanga (L.) Willd) RHIZOME EXTRACT

Putranti

Dewi²,

Widiyastuti³

2018

J.Pharm.Sci.Community

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The lengkuas rhizome has an antifungal activity. The non-specific parameters for extracts of lengkuas rhizome need to be standardized to obtain the extracts with consistent good quality. The lengkuas rhizome extract emulgel topical preparations are easily mixed with active substances that are hydrophobic or hydrophilic. This study aims to obtain a lengkuas rhizome extract emulgel formula that has good quality and good physical properties. Extraction of lengkuas rhizome was obtained using a maceration method with 96% ethanol solvent. The extract is standardized by non-specific parameters. After that, the extract was formulated in the form of emulgel preparation with 10% concentration. The physical properties of emulgel were evaluated. The results of the study showed that the extract yield is of (14.66±0.056)%; powder drying shrinkage (8.63±0.134)%; extract water rate (5±0)%; powder total ash rate (3.24±0.017)%; and extract (1.30±0.035)%; acid-insoluble ash rate powder (2.66±0.10)%; and extract (0.87±0.031)%; extract type weight 1.01; and the physical properties of emulgel preparations were homogeneous emulgel, semisolid form, light brown color, distinctive smell of lengkuas rhizome extract, stable at 5 o C and 25 o C for 24 hours; pH 7; spreadability (2.45±0.03) g.cm.s-1; stickiness (8.80±0.72) seconds; o/w emulsion type; and viscosity (1.37±0.22) Pa.s. This study obtained extracts of lengkuas rhizomes that meet the requirements of non-specific parameter standardization in general and the formulation of lengkuas rhizome extract emulgel had good physical properties. Keywords: lengkuas rhizome extract, non-specific parameter standardization, emulgel ABSTRAK Rimpang lengkuas memiliki aktivitas sebagai antifungi. Ekstrak rimpang lengkuas perlu dilakukan standardisasi parameter non spesifik untuk memperoleh sediaan yang terjamin mutunya secara konsisten. Sediaan topikal emulgel ekstrak rimpang lengkuas merupakan sediaan yang mudah bercampur dengan zat aktif yang bersifat hidrofob atau hidrofil. Penelitian ini bertujuan untuk mendapatkan formula emulgel ekstrak rimpang lengkuas yang memiliki mutu yang baik serta sifat fisik yang baik. Ekstraksi rimpang lengkuas diperoleh dengan menggunakan metode maserasi dengan pelarut etanol 96%. Ekstrak distandardisasi dengan parameter non spesifik. Selanjutnya ekstrak diformulasikan dalam bentuk sediaan emulgel dengan konsentrasi 10%. Emulgel dievaluasi uji sifat fisik. Hasil penelitian diperoleh rendemen ekstrak (14,66±0,056)%; susut pengeringan serbuk (8,63±0,134)%; kadar air ekstrak (5±0)%; kadar abu total serbuk (3,24±0,017)%; dan ekstrak (1,30±0,035)%; kadar abu tidak larut asam serbuk (2,66±0,10)%; dan ekstrak (0,87±0,031)%; bobot jenis ekstrak 1,01; dan uji sifat fisik sediaan emulgel diperoleh emulgel homogen, bentuk semisolid, berwarna coklat muda, bau khas ekstrak rimpang lengkuas, stabil pada suhu 5 o C dan 25 o C selama 24 jam; pH 7; daya sebar (2,45±0,03) g.cm.s-1; daya lekat (8,80±0,72) detik; tipe emulsi o/w; dan viskositas (1,37±0,22) Pa.s. Penelitian ini diperoleh e...

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Section: Phenol Compound Screening Testmentioning

confidence: 73%

“…1 mL of the produced solution was taken and then 2 drops of 5% FeCl3 solution were added. Positive reactions are indicated by the formation of green or yellowish green color (Nugrahani et al, 2016).…”

Section: Phenol Compound Screening Testmentioning

confidence: 99%

STANDARDIZATION OF EXTRACT AND CHARACTERIZATION OF EMULGEL FORMULA OF LENGKUAS (Alpinia galanga (L.) Willd) RHIZOME EXTRACT

Putranti

Dewi²,

Widiyastuti³

2018

J.Pharm.Sci.Community

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“…The appearance of foam characterized saponin in the sample after shaking, and the foam was stable for ± 10 minutes. The emergence of foam indicates the presence of hydrolyzed glycosides (Nugrahani et al 2016). The reaction is as in The results of the phytochemical assay on nhexane, ethyl acetate, and methanol extract from frangipani flowers can be seen in Table 2.…”

Section: Phytochemicalmentioning

confidence: 98%

Characterization and antioxidant assay of yellow frangipani flower (Plumeria alba) extract

Fathoni

Rudiana

Adawiah

2019

JPKim

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Yellow frangipani flowers (Plumeria alba) are plants that commonly found in the tropics, including Indonesia. Frangipani utilization has not optimum and research about it has not many conducted. This study aims to characterize and test the antioxidant activity of frangipani flower extract. The ex traction conducted by maceration method using n-hexane, ethyl acetate, and methanol as solvents. Characterization includes phytochemicals assay (alkaloids, flavonoids, terpenoids, phenolic hydroquinone, tannin-polyphenols, and saponins), total phenolic assay, and total flavonoid assay. Antioxidant test using DPPH radical scavenging assay. The results of the characterization showed that frangipani flower extract positively contained alkaloid, flavonoids, tannins compounds in all solvent phases. Terpenoids are positive in n-hexane and ethyl acetate extract, while saponins are positive in methanol extract. The total phenolic content of n-hexane, ethyl acetate, and methanol extract were 3.6 mgGAE/g; 27.74 mgGAE/g; and 35.23 mgGAE/g. The total flavonoid content of n-hexane, ethyl acetate, and methanol extract were respectively 0.8 mgQE/g; 12.18 mgQE/g; 19.9 mgQE/g. The strongest antioxidant activity is possessed by ethyl extract, followed by methanol extract, and the last are n-hexane extract.

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“…Qualitative determination of phytochemical compound included flavonoids [13], phenolic [14], alkaloids [15], steroids and triterpenoids [15], terpenoids [16], tannins [15], saponin [15] [17], and glycosides [18].…”

Section: Qualitative Determination Of Phytochemical Compoundmentioning

confidence: 99%

Ethyl Acetate Extract of Red Melinjo (Gnetum Gnemon L.) Peel as Antibacterial Compound

Parhusip¹,

Angel²,

Anugrahati³

et al. 2020

Proceedings of the 5th International Conference on Food, Agriculture and Natural Resources (FANRes 2019)

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Melinjo (Gnetum gnemon L.) is a native plant in Indonesia. Melinjo peel is generally disposed of, although it contains tannin, flavonoid and saponin, which can be used as antimicrobial compounds. The purpose of this research was to analyze the antimicrobial activity of melinjo peel extract. Maceration method was conducted to extract the melinjo peel, using ethyl acetate as the solvent. The extract at concentration of 4, 8, 12, and 16% (w/v) could inhibit Escherichia coli ATCC 8739, Bacillus cereus ATCC 10876, and Pseudomonas aeruginosa ATCC 9027, but could not inhibit Rhizopus oligosporus ATCC 22959. The extract MIC and MBC value was ranged from 0.50-0.69% and 2.00-2.76%, respectively. Alkaloids, saponin, phenolic, flavonoids and glycosides were found in the extract. The inhibition of selected extract (12%) had a similar level to 1000 ppm Colistin against E. coli and P. aeruginosa. Low pH (pH 4) increased the inhibition of the extract, while neutral pH decreased the inhibition. Heating extract at 65 0 C for 30 minutes increased the inhibition, whereas heating at 75, 85, and 95 0 C decreased the inhibition. The present of salt and sugar at concentration of 1-5% and 10-50%, respectively, increased the inhibition. The extract could damage cell morphology and was confirmed by the presence of ions (Ca 2+ , K + , dan Mg 2+) outside of the cells.

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SKRINING FITOKIMIA DARI EKSTRAK BUAH BUNCIS (Phaseolus vulgaris L) DALAM SEDIAAN SERBUK

Cited by 36 publications

References 0 publications

STANDARDIZATION OF EXTRACT AND CHARACTERIZATION OF EMULGEL FORMULA OF LENGKUAS (Alpinia galanga (L.) Willd) RHIZOME EXTRACT

STANDARDIZATION OF EXTRACT AND CHARACTERIZATION OF EMULGEL FORMULA OF LENGKUAS (Alpinia galanga (L.) Willd) RHIZOME EXTRACT

Characterization and antioxidant assay of yellow frangipani flower (Plumeria alba) extract

Ethyl Acetate Extract of Red Melinjo (Gnetum Gnemon L.) Peel as Antibacterial Compound

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