Skrining Efektivitas Ekstrak Tanaman Herbal sebagai Anthelmintik terhadap Telur dan Larva Nematoda serta Cacing Haemonchus contortus secara In-Vitro

Abstract

Hemonchosis is caused by the nematode of Haemonchus contortus, which can cause high economic losses. The most common treatment for helminthiasis is by broad-spectrum chemical anthelmintics, but if used continuously for a long time can cause resistance and residue to livestock products, which pose a serious threat to livestock production. This study aims to conduct screening tests on herbal plants that can be used as effective and efficient nematode worm medicines. Bitter melon seeds (Momordica charantia L.), white ginger (Curcuma zedoaria Rosce), noni fruit (Morinda citrifolia), cassava leaves (Manihot uttilissima), avocado seeds (Persea americana Mill), papaya leaves (Carica papaya L.), katuk leaves (Sauropus androgynus L. Merr), areca nut (Areca catechu), garlic (Allium sativum) and gum gambier (Uncaria gambier Roxb) were extracted and tested for phytochemistry at the Spice and Drug Research Institute (Balittro). Screening tests were carried out using 10 herbal plant extracts against eggs, larvae of nematode and H. contortus adult worms using 1% DMSO media in vitro. The results showed that sequentially 5 herbs of avocado seeds, white Intersection, momordica seeds, noni fruit and areca nut potential as nematode worm medicines in ruminants were effective and efficient.