Skipping the Lymphoscintigraphy Step During Sentinel Node Procedures in Breast Cancer: What Information Are We Missing?

Hindié, Elif

doi:10.1200/jco.19.01612

JCO

2019

DOI: 10.1200/jco.19.01612

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Skipping the Lymphoscintigraphy Step During Sentinel Node Procedures in Breast Cancer: What Information Are We Missing?

Elif Hindié¹

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“…Hindié 1 suggested that LSG may provide additional value in the subgroup of patients with one to three involved axillary LNs by identifying those who derive greater benefit from IMN irradiation. Several prospective trials conducted in patients who predominantly had zero to three involved axillary LNs have shown improved oncologic outcomes with regional nodal irradiation (RNI), including IMNs.…”

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confidence: 99%

Reply to E. Hindié and A.K. Goel et al

Holtschmidt

Küemmel

Krug

et al. 2019

JCO

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We appreciate the comments of Hindié 1 and Goel et al 2 in their letters to the editor in response to our recent article in Journal of Clinical Oncology titled "Prospective, Multicenter, Randomized Phase III Trial Evaluating the Impact of Lymphoscintigraphy as Part of Sentinel Node Biopsy in Early Breast Cancer: SenSzi (GBG80) Trial." 3 Our study concerned the impact of lymphoscintigraphy (LSG) on the accuracy of surgical axillary staging with sentinel lymph node biopsy (SLNB) in early breast cancer in everyday practice. 3 Because the letters refer to quite different topics associated with the role of LSG for SLNB in patients with breast cancer, we will respond to each one separately.When SLNB was introduced to routine care, surgeons lacked familiarity with the challenging new technique and had different awareness of the need to avoid unnecessary trauma. In our opinion, the speed of the procedure, detection rate, and extent of surgical trauma are crucially dependent on the experience of the breast surgeon and, to a lesser extent, on preoperative imaging. 4 We thus believe that the findings from 2005, 5 as cited by Hindié, 1 do not apply to the contemporary clinical situation. Transcutaneous gamma probe hot-spot detection and dual-tracer marking are commonly available to determine the optimal incision site.

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confidence: 99%

Reply to E. Hindié and A.K. Goel et al

Holtschmidt

Küemmel

Krug

et al. 2019

JCO

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Skipping the Lymphoscintigraphy Step During Sentinel Node Procedures in Breast Cancer: What Information Are We Missing?

Cited by 1 publication

References 9 publications

Reply to E. Hindié and A.K. Goel et al

Reply to E. Hindié and A.K. Goel et al

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