Skin Signs as the Presenting Manifestation of Severe Nutritional Deficiency

Kuhl, John T.; Davis, Mark D. P.; Kalaaji, Amer N.; Kamath, Patrick S.; Hand, Jennifer L.; Peine, Craig J.

doi:10.1001/archderm.140.5.521

Cited by 18 publications

(11 citation statements)

References 15 publications

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“…Presentation of cystic fibrosis with dermatitis is rare, with only 21 previously reported cases [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16]20,21]. The exact aetiology is not known, however it is postulated to represent the end product of multiple nutritional and metabolic derangements, resulting in a kwashiorkor-like state.…”

Section: Discussionmentioning

confidence: 99%

‘Peeling paint’ dermatitis as a presenting sign of cystic fibrosis

O’Regan

Canny

Irvine

2006

Journal of Cystic Fibrosis

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Presentation of cystic fibrosis with a rash is rare, with only 19 previously reported cases. This unusual presentation is associated with false negative sweat tests, delays in diagnosis and considerable mortality. Multiple nutritional deficiencies, the aberrant production of prostaglandins and free-radical mediated damage have been implicated in the pathogenesis of this kwashiorkor-like dermatitis. In spite of the rarity of this presentation, recognition of the rash is important, not only to expedite the diagnosis, but also to gain insight into the disease. We present a further case to highlight this unusual presentation and discuss potential pathophysiological mechanisms.

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Section: Discussionmentioning

confidence: 99%

‘Peeling paint’ dermatitis as a presenting sign of cystic fibrosis

O’Regan

Canny

Irvine

2006

Journal of Cystic Fibrosis

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“…1 Unfortunately, kwashiorkor continues to be reported in infants in developed countries who are fed protein-poor diets, including 4 infants in the medical literature who developed the disease while on rice beverageebased diets. [5][6][7][8] Two other cases received attention in the popular press after Rice Dream-associated kwashiorkor in infants led to the prosecution of the infants' parents or guardians. In an Australian case, parents of a 5 and a half-monthold girl who died of kwashiorkor were charged (although not convicted) with manslaughter in 2000.…”

Section: Discussionmentioning

confidence: 99%

“…Other reported laboratory abnormalities in infants with kwashiorkor include anemia (seen in both of our patients) and transaminitis (seen in patient 2). 5,6,8 Deficiencies in essential fatty acids and biotin as well as other malabsorption syndromes should also be considered in the differential diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Rice nightmare: Kwashiorkor in 2 Philadelphia-area infants fed Rice Dream beverage

Katz¹,

Mahlberg

Honig

et al. 2005

Journal of the American Academy of Dermatology

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“…Regarding the clinical manifestations secondary to the use of rice beverages, the information on 17 cases is given in supplemental table IV (http://www.nutricionhospitalaria.org/wp-content/ uploads/2014/11/931-material-suplementario.pdf) (5,6,(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34). The principal nutritional consequence in infants of consumption of rice beverages instead of infant formula is protein malnutrition or kwashiorkor, reported in 14 of 17 cases, with clinical data of hypoalbuminemia, edema and rash.…”

Section: Consumption Of Pbbs and Nutritional Diseasementioning

confidence: 99%

The nutritional limitations of plant-based beverages in infancy and childhood

Vitoria¹

2017

Nutr Hosp

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The nutritional limitations of plant-based beverages in infancy and childhood Limitaciones nutricionales de las bebidas vegetales en la lactancia y la infancia ResumenLa lactancia materna, la fórmula infantil y la leche de vaca son alimentos básicos en la nutrición del lactante. Sin embargo, cada vez son reemplazados, total o parcialmente, por bebidas vegetales. Se ha revisado la composición de 164 bebidas vegetales disponibles en España a partir del etiquetado nutricional del envase y de las páginas web de los fabricantes. Se ha comparado con la composición de la leche de vaca y de la fórmula infantil. Además, se ha revisado la patología nutricional asociada con el consumo de bebidas vegetales en lactantes y niños mediante una búsqueda bibliográfica en Medline y EMBASE desde 1990 basada en las palabras clave "plant-based beverages" o "rice beverages" o "almond beverages" o "soy beverages" y "infant" o "child". Se describe la composición nutricional de 54 bebidas de soja, 24 bebidas de arroz, 22 bebidas de almendras, 31 bebidas de avena, 6 bebidas de coco, 12 bebidas misceláneas y 15 bebidas mixtas. Se han publicado al menos 30 casos de patología nutricional en niños asociadas con un consumo casi exclusivo de bebidas vegetales. Se ha observado una asociación característica entre la bebida de soja y el raquitismo, la bebida de arroz y el kwashiorkor, y la bebida a base de almendras y la alcalosis metabólica. La calidad nutricional de las bebidas vegetales es menor que la leche de vaca y la fórmula infantil, por lo que no son una alternativa nutricional. El uso predominante o exclusivo de estas bebidas en la alimentación infantil puede conducir a graves riesgos nutricionales. En el caso de una alimentación no exclusiva con estas bebidas, el pediatra debe ser consciente de los riesgos y limitaciones nutricionales de estas bebidas para complementar sus deficiencias con otros alimentos. AbstractBreastfeeding, infant formula and cow's milk are basic foods in infant nutrition. However, they are being increasingly replaced either totally or partially by plant-based beverages. The composition of 164 plant-based beverages available in Spain was reviewed based on the nutritional labeling of the package and the manufacturers' webpages. This was compared to the composition of cow's milk and infant formula. In addition, the nutritional disease associated with consumption of plant-based beverages in infants and children was reviewed by means of a literature search in Medline and Embase since 1990 based on the key words "plant-based beverages" or "rice beverages" or "almond beverages" or "soy beverages" and "infant" or "child". The nutritional composition of 54 soy beverages, 24 rice beverages, 22 almond beverages, 31 oat beverages, 6 coconut beverages, 12 miscellaneous beverages and 15 mixed beverages was described. At least 30 cases of nutritional disease in children associated with nearly exclusive consumption of plant-based beverages have been published. A characteristic association has been observed between soy beverage a...

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Skin Signs as the Presenting Manifestation of Severe Nutritional Deficiency

Cited by 18 publications

References 15 publications

‘Peeling paint’ dermatitis as a presenting sign of cystic fibrosis

‘Peeling paint’ dermatitis as a presenting sign of cystic fibrosis

Rice nightmare: Kwashiorkor in 2 Philadelphia-area infants fed Rice Dream beverage

The nutritional limitations of plant-based beverages in infancy and childhood

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