Skin reactions to primary irritants and predisposition to eczema

Björnberg, Alf

doi:10.1111/j.1365-2133.1974.tb13081.x

Cited by 46 publications

(45 citation statements)

References 3 publications

(3 reference statements)

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“…Lammintausta, Maibach, and Wilson 60 and Holst and Moller 61 found no gender-related differences in experimental ICD induced by sodium lauryl sulfate. In another study, 62 there were no gender-related differences after exposure to such irritants as sodium lauryl sulfate, benzalkonium chloride, soap, hydrochloric acid, cantharidin, and croton oil in patients with hand eczema and in normal control subjects. Thus whether gender truly has an impact on the development of ICD is unclear.…”

Section: Agementioning

confidence: 94%

Occupational contact dermatitis: Etiology, prevalence, and resultant impairment/disability

Belsito

2005

Journal of the American Academy of Dermatology

143

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Section: Agementioning

confidence: 94%

Occupational contact dermatitis: Etiology, prevalence, and resultant impairment/disability

Belsito

2005

Journal of the American Academy of Dermatology

143

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“…Augener et al (58) observed that the numbers of circulating T-lymphocytes decreased more than 50% in the age group [67][68][69][70][71][72][73][74][75][76][77][78][79][80][81][82][83] years, compared with children (3)(4)(5)(6)(7)(8)(9)(10)(11)(12) years), whereas the number of Blymphocytes remained constant. The decline in Tlymphocytes is a plausible explanation for the decreased recall-delayed hypersensitivity response.…”

Section: (Iii) Langerhans Cells and Circulating T-lymphocytes In The mentioning

confidence: 99%

Effect of age and sex on the induction and elicitation of allergic contact dermatitis

Kwangsukstith

Maibach

1995

Contact Dermatitis

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This article reviews the effect of age and sex on the induction and elicitation of allergic contact dermatitis (ACD). We found that the incidence of ACD in childhood is lower than in adults; this may be explained by less exposure to allergens, lack of immune response and limited patch test studies in this age group. In the elderly, there is an age-dependent decrease in the incidence of ACD, with decreased sensitization to new allergens and waning responses in previously sensitized subjects. There is extensive controversy about the effect of sex differences in ACD. The induction phases of ACD in both sexes are different due to differences in exposure to the allergens from occupations, habits and cultures. Differences in elicitation phases of ACD in both sexes are not confirmed. Women tend to have a higher incidence of ACD and higher immunologic response to exposure allergens than men. Thus we can only imprecisely define the effect of age and sex on the induction and elicitation of ACD. Further prospective studies should be done to answer these questions.

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“…Several studies of irritant contact dermatitis have used BAK 0.5%, 48Y50 although concentrations in other reports on irritants in patients with eczema ranged from 0.1% to 2%. 51,52 When used as an irritant or nonsensitizer in sensitization studies, concentrations range from 0.2% for in vitro human epidermis testing 53 to 2% for murine lymph node testing. 54 It is therefore not surprising that in a predictive test for irritancy, BAK 7.5% and 10% were found to be irritating during a human 4-hour patch test.…”

Section: Resultsmentioning

confidence: 99%