Skin microbiota analysis in a patient and its role in clinical practice

Abstract

The skin is structurally a complex barrier organ that forms an original dynamic ecosystem colonized by a wide range of bacteria, fungi, viruses, and mites. The skin microbiome plays an important role in maintaining homeostasis and the state of local immunity and affects pathogenic microorganisms and skin barrier function through bacterial enzyme production. The most frequent and common infectious skin lesions are pyoderma, atopic dermatitis, psoriasis, hidradenitis suppurativa, acne vulgaris, rosacea, seborrheic dermatitis, various mycoses, as well as bacterial and fungal folliculitis. A detailed study of the impact of homeostatic balance on the health of the skin plays an important role in the diagnosis and treatment of skin diseases. Further investigations and deciphering bacteria, fungi, and viruses colonizing the skin will contribute to more effective diagnosis and identification of associations between the microbiota and the occurrence of various diseases, as well as to the development of more effective methods for their treatment, which is of great importance in clinical practice.